Mitochondrial genome instability: its potential role in biomarker discovery for brain tumorigenesis
Background: Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA (mtDNA) damage and lead to carcinogenesis. MtDNA 4,977-bp deletion as well as alteration in mtDNA copy number have been implicated in various types of human cancers....
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| Format: | Monograph |
| Language: | en |
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Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
2017
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| Online Access: | http://eprints.usm.my/57035/1/DR%20ABDUL%20AZIZ%20MOHAMED%20YUSOFF-Eprints.pdf http://eprints.usm.my/57035/ |
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