Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel

The ionic pH sensitive polymer contains acid groups (carboxylic or sulphonic) or basic groups (ammonium salts) in which response to pH changes in the biological environment. The pH responsive poly(ethylene glycol)/poly(acrylic acid) (PEG/PAA) hydrogel was prepared by using free radical polymerizatio...

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Main Author: Salleh, Syahira Amira Mohd
Format: Monograph
Language:en
Published: Universiti Sains Malaysia 2017
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Online Access:http://eprints.usm.my/52497/1/Fabrication%20And%20Characterization%20Of%20Ph-Responsive%20Poly%28Ethylene%20Glycol%29%20Methyl%20Ether%20Methacrylates_Poly%28Acrylic%20Acid%29%20Hydrogel_Syahira%20Amira%20%20Mohd%20Salleh_B1_2017.pdf
http://eprints.usm.my/52497/
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author Salleh, Syahira Amira Mohd
author_facet Salleh, Syahira Amira Mohd
author_sort Salleh, Syahira Amira Mohd
building Hamzah Sendut Library
collection Institutional Repository
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
continent Asia
country Malaysia
description The ionic pH sensitive polymer contains acid groups (carboxylic or sulphonic) or basic groups (ammonium salts) in which response to pH changes in the biological environment. The pH responsive poly(ethylene glycol)/poly(acrylic acid) (PEG/PAA) hydrogel was prepared by using free radical polymerization with a two-step sequential network formation process. The sample prepared are single network of PEG, PAA and hybrid of PEG/PAA hydrogels. The hydrogels were characterized to determine the chemical and mechanical properties as well as the responsive ability of hydrogels towards pH at different pH solution. The Fourier Transform Infrared (FTIR) Spectra showed that PEG/PAA hydrogels synthesized was successfully achieved as C-O-C stretching vibration peak was present. Compression test was used to study the mechanical strength of PEG, PAA and PEG/PAA hydrogels. The mechanical test results showed that the mechanical strength of PEG/PAA hydrogel were considerably greater than the individual polymer network. In addition, the pH responsive behaviour were also studied and it was found that the swelling ratio was increased with the increasing of pH. The result from swelling-deswelling kinetics at pH 3 and pH 7 showed good swelling/deswelling reversibility compared than swelling-deswelling kinetics at pH 10 and pH 7.
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institution Universiti Sains Malaysia
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publisher Universiti Sains Malaysia
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spelling my.usm.eprints.52497 http://eprints.usm.my/52497/ Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel Salleh, Syahira Amira Mohd T Technology TA401-492 Materials of engineering and construction. Mechanics of materials The ionic pH sensitive polymer contains acid groups (carboxylic or sulphonic) or basic groups (ammonium salts) in which response to pH changes in the biological environment. The pH responsive poly(ethylene glycol)/poly(acrylic acid) (PEG/PAA) hydrogel was prepared by using free radical polymerization with a two-step sequential network formation process. The sample prepared are single network of PEG, PAA and hybrid of PEG/PAA hydrogels. The hydrogels were characterized to determine the chemical and mechanical properties as well as the responsive ability of hydrogels towards pH at different pH solution. The Fourier Transform Infrared (FTIR) Spectra showed that PEG/PAA hydrogels synthesized was successfully achieved as C-O-C stretching vibration peak was present. Compression test was used to study the mechanical strength of PEG, PAA and PEG/PAA hydrogels. The mechanical test results showed that the mechanical strength of PEG/PAA hydrogel were considerably greater than the individual polymer network. In addition, the pH responsive behaviour were also studied and it was found that the swelling ratio was increased with the increasing of pH. The result from swelling-deswelling kinetics at pH 3 and pH 7 showed good swelling/deswelling reversibility compared than swelling-deswelling kinetics at pH 10 and pH 7. Universiti Sains Malaysia 2017-06-01 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/52497/1/Fabrication%20And%20Characterization%20Of%20Ph-Responsive%20Poly%28Ethylene%20Glycol%29%20Methyl%20Ether%20Methacrylates_Poly%28Acrylic%20Acid%29%20Hydrogel_Syahira%20Amira%20%20Mohd%20Salleh_B1_2017.pdf Salleh, Syahira Amira Mohd (2017) Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel. Project Report. Universiti Sains Malaysia, Pusat Pengajian Kejuruteraan Bahan Sumber Mineral. (Submitted)
spellingShingle T Technology
TA401-492 Materials of engineering and construction. Mechanics of materials
Salleh, Syahira Amira Mohd
Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title_full Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title_fullStr Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title_full_unstemmed Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title_short Fabrication And Characterization Of Ph-Responsive Poly(Ethylene Glycol) Methyl Ether Methacrylates_Poly(Acrylic Acid) Hydrogel
title_sort fabrication and characterization of ph-responsive poly(ethylene glycol) methyl ether methacrylates_poly(acrylic acid) hydrogel
topic T Technology
TA401-492 Materials of engineering and construction. Mechanics of materials
url http://eprints.usm.my/52497/1/Fabrication%20And%20Characterization%20Of%20Ph-Responsive%20Poly%28Ethylene%20Glycol%29%20Methyl%20Ether%20Methacrylates_Poly%28Acrylic%20Acid%29%20Hydrogel_Syahira%20Amira%20%20Mohd%20Salleh_B1_2017.pdf
http://eprints.usm.my/52497/
url_provider http://eprints.usm.my/