Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and...
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| Format: | Thesis |
| Language: | en |
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2021
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| Online Access: | http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf http://eprints.usm.my/52192/ |
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| author | Ng, Weng Zhun |
| author_facet | Ng, Weng Zhun |
| author_sort | Ng, Weng Zhun |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group |
| format | Thesis |
| id | my.usm.eprints.52192 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2021 |
| record_format | eprints |
| spelling | my.usm.eprints.52192 http://eprints.usm.my/52192/ Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety Ng, Weng Zhun QC1 Physics (General) A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group 2021-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf Ng, Weng Zhun (2021) Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety. Masters thesis, Perpustakaan Hamzah Sendut. |
| spellingShingle | QC1 Physics (General) Ng, Weng Zhun Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title | Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_full | Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_fullStr | Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_full_unstemmed | Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_short | Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_sort | synthesis, x-ray structure characterization and antioxidant activities of some chalcone derivatives containing 2-chlorothiophene moiety |
| topic | QC1 Physics (General) |
| url | http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf http://eprints.usm.my/52192/ |
| url_provider | http://eprints.usm.my/ |