Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease
Using an inducible Drosophila AD model by human Aβ42 expression with UAS/GAL4 system, the study was carried out to evaluate the effects of probiotic administration on the survival and mobility of female Drosophila melanogaster with AD. Evaluated by survival assay, the administration of L. fermentum...
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| Format: | Monograph |
| Language: | en |
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Universiti Sains Malaysia
2020
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| Online Access: | http://eprints.usm.my/49507/1/Lim%20Hui%20Ting.pdf%20cut.pdf http://eprints.usm.my/49507/ |
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| _version_ | 1834504400906747904 |
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| author | Lim, Hui Ting |
| author_facet | Lim, Hui Ting |
| author_sort | Lim, Hui Ting |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Using an inducible Drosophila AD model by human Aβ42 expression with UAS/GAL4 system, the study was carried out to evaluate the effects of probiotic administration on the survival and mobility of female Drosophila melanogaster with AD. Evaluated by survival assay, the administration of L. fermentum DR9 for 24 days improved survival by increasing the survival percentage of female D. melanogaster AD model, as compared to the untreated control. Evaluated by the negative-geotaxis climbing assay, the administration of L. fermentum DR9 for 20 days improved the mobility of female D. melanogaster AD model in terms of climbing ability and climbing speed, by declining at a slower and more constant rate as compared to the untreated control. |
| format | Monograph |
| id | my.usm.eprints.49507 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2020 |
| publisher | Universiti Sains Malaysia |
| record_format | eprints |
| spelling | my.usm.eprints.49507 http://eprints.usm.my/49507/ Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease Lim, Hui Ting T1-995 Technology(General) Using an inducible Drosophila AD model by human Aβ42 expression with UAS/GAL4 system, the study was carried out to evaluate the effects of probiotic administration on the survival and mobility of female Drosophila melanogaster with AD. Evaluated by survival assay, the administration of L. fermentum DR9 for 24 days improved survival by increasing the survival percentage of female D. melanogaster AD model, as compared to the untreated control. Evaluated by the negative-geotaxis climbing assay, the administration of L. fermentum DR9 for 20 days improved the mobility of female D. melanogaster AD model in terms of climbing ability and climbing speed, by declining at a slower and more constant rate as compared to the untreated control. Universiti Sains Malaysia 2020-06 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/49507/1/Lim%20Hui%20Ting.pdf%20cut.pdf Lim, Hui Ting (2020) Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease. Other. Universiti Sains Malaysia. (Submitted) |
| spellingShingle | T1-995 Technology(General) Lim, Hui Ting Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title | Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title_full | Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title_fullStr | Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title_full_unstemmed | Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title_short | Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease |
| title_sort | effects of a lactobacilli probiotic on survival and mobility of female drosophila melanogaster with alzheimer’s disease |
| topic | T1-995 Technology(General) |
| url | http://eprints.usm.my/49507/1/Lim%20Hui%20Ting.pdf%20cut.pdf http://eprints.usm.my/49507/ |
| url_provider | http://eprints.usm.my/ |