Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and sti...
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| Format: | Thesis |
| Language: | en |
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2017
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| Online Access: | http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf http://eprints.usm.my/45376/ |
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| author | Farsi, Elham |
| author_facet | Farsi, Elham |
| author_sort | Farsi, Elham |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity. |
| format | Thesis |
| id | my.usm.eprints.45376 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2017 |
| record_format | eprints |
| spelling | my.usm.eprints.45376 http://eprints.usm.my/45376/ Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves Farsi, Elham L7-991 Education (General) Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity. 2017-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf Farsi, Elham (2017) Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | L7-991 Education (General) Farsi, Elham Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title | Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title_full | Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title_fullStr | Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title_full_unstemmed | Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title_short | Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves |
| title_sort | nephroprotective effect of clinacanhus nutans, orthosiphon stamineus, and syzyguim camponulatum leaves against cisplatin-induced nephrotoxcity; and safety asseement of clinacathus nutans leaves |
| topic | L7-991 Education (General) |
| url | http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf http://eprints.usm.my/45376/ |
| url_provider | http://eprints.usm.my/ |