The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies
Pineal melatonin biosynthesis is regulated by the circadian clock located in the suprachiasmatic nucleus of the hypothalamus. Melatonin has been found to modulate the learning and memory process in human as well as in animals. Endogenous melatonin modulates the process of newly acquired informa...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | en |
| Published: |
Charles University - First Faculty of Medicine
2016
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/45337/1/Potential%20Role%20of%20Melatonin%20on%20Memory%20Function.pdf http://eprints.usm.my/45337/ https://fb.cuni.cz/volume-62-2016-no-5#articFB2016A0022 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1834503301644681216 |
|---|---|
| author | Zakaria, Rahimah Ahmad, Asma Hayati Othman, Zahiruddin |
| author_facet | Zakaria, Rahimah Ahmad, Asma Hayati Othman, Zahiruddin |
| author_sort | Zakaria, Rahimah |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Pineal melatonin biosynthesis is regulated
by the circadian clock located in the suprachiasmatic
nucleus of the hypothalamus. Melatonin has been
found to modulate the learning and memory process
in human as well as in animals. Endogenous melatonin
modulates the process of newly acquired information
into long-term memory, while melatonin
treatment has been found to reduce memory deficits
in elderly people and in various animal models.
However, the mechanisms mediating the enhancing
effect of melatonin on memory remain elusive. This
review intends to explore the possible mechanisms
by looking at previous data on the effects of melatonin
treatment on memory performance in rodents. |
| format | Article |
| id | my.usm.eprints.45337 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2016 |
| publisher | Charles University - First Faculty of Medicine |
| record_format | eprints |
| spelling | my.usm.eprints.45337 http://eprints.usm.my/45337/ The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies Zakaria, Rahimah Ahmad, Asma Hayati Othman, Zahiruddin RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Pineal melatonin biosynthesis is regulated by the circadian clock located in the suprachiasmatic nucleus of the hypothalamus. Melatonin has been found to modulate the learning and memory process in human as well as in animals. Endogenous melatonin modulates the process of newly acquired information into long-term memory, while melatonin treatment has been found to reduce memory deficits in elderly people and in various animal models. However, the mechanisms mediating the enhancing effect of melatonin on memory remain elusive. This review intends to explore the possible mechanisms by looking at previous data on the effects of melatonin treatment on memory performance in rodents. Charles University - First Faculty of Medicine 2016 Article PeerReviewed application/pdf en http://eprints.usm.my/45337/1/Potential%20Role%20of%20Melatonin%20on%20Memory%20Function.pdf Zakaria, Rahimah and Ahmad, Asma Hayati and Othman, Zahiruddin (2016) The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies. Folia Biologica (Praha), 62. pp. 181-187. ISSN 2533-7602 https://fb.cuni.cz/volume-62-2016-no-5#articFB2016A0022 |
| spellingShingle | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Zakaria, Rahimah Ahmad, Asma Hayati Othman, Zahiruddin The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies |
| title | The Potential Role of Melatonin on Memory Function:
Lessons from Rodent Studies |
| title_full | The Potential Role of Melatonin on Memory Function:
Lessons from Rodent Studies |
| title_fullStr | The Potential Role of Melatonin on Memory Function:
Lessons from Rodent Studies |
| title_full_unstemmed | The Potential Role of Melatonin on Memory Function:
Lessons from Rodent Studies |
| title_short | The Potential Role of Melatonin on Memory Function:
Lessons from Rodent Studies |
| title_sort | potential role of melatonin on memory function:
lessons from rodent studies |
| topic | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| url | http://eprints.usm.my/45337/1/Potential%20Role%20of%20Melatonin%20on%20Memory%20Function.pdf http://eprints.usm.my/45337/ https://fb.cuni.cz/volume-62-2016-no-5#articFB2016A0022 |
| url_provider | http://eprints.usm.my/ |