Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for fur...
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| Format: | Thesis |
| Language: | en |
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2014
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| Online Access: | http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf http://eprints.usm.my/45075/ |
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| author | Kumar, Thiviyaa M. Othaya |
| author_facet | Kumar, Thiviyaa M. Othaya |
| author_sort | Kumar, Thiviyaa M. Othaya |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by
LocaRNA software. |
| format | Thesis |
| id | my.usm.eprints.45075 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2014 |
| record_format | eprints |
| spelling | my.usm.eprints.45075 http://eprints.usm.my/45075/ Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi Kumar, Thiviyaa M. Othaya R735-854 Medical education. Medical schools. Research Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by LocaRNA software. 2014-12 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf Kumar, Thiviyaa M. Othaya (2014) Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R735-854 Medical education. Medical schools. Research Kumar, Thiviyaa M. Othaya Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title | Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_full | Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_fullStr | Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_full_unstemmed | Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_short | Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_sort | functional characterization of styr-3 non-protein-coding rna (npcrna) in salmonella enterica serovar typhi |
| topic | R735-854 Medical education. Medical schools. Research |
| url | http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf http://eprints.usm.my/45075/ |
| url_provider | http://eprints.usm.my/ |