Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates
Bioconjugates (PNIPAAm−graft−DNA) of poly(N-isopropylacrylamide) (PNIPAAm) grafted with single-stranded (ss) DNA were synthesized via radical copolymerization. The bioconjugates self-assembled above its lower critical solution temperature (LCST) in aqueous solution to form micelle-like colloidal nan...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | en |
| Published: |
2012
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/44882/1/OOI%20WEI%20YANG.pdf http://eprints.usm.my/44882/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1834503187317391360 |
|---|---|
| author | Ooi, Wei Yang |
| author_facet | Ooi, Wei Yang |
| author_sort | Ooi, Wei Yang |
| building | Hamzah Sendut Library |
| collection | Institutional Repository |
| content_provider | Universiti Sains Malaysia |
| content_source | USM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Bioconjugates (PNIPAAm−graft−DNA) of poly(N-isopropylacrylamide) (PNIPAAm) grafted with single-stranded (ss) DNA were synthesized via radical copolymerization. The bioconjugates self-assembled above its lower critical solution temperature (LCST) in aqueous solution to form micelle-like colloidal nanoparticles. When the ssDNA of the nanoparticle hybridizes with complementary DNA, the particles aggregate above a certain threshold of salt concentration with drastically increased turbidity in solution. |
| format | Thesis |
| id | my.usm.eprints.44882 |
| institution | Universiti Sains Malaysia |
| language | en |
| publishDate | 2012 |
| record_format | eprints |
| spelling | my.usm.eprints.44882 http://eprints.usm.my/44882/ Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates Ooi, Wei Yang QH1 Natural history (General - Including nature conservation, geographical distribution) Bioconjugates (PNIPAAm−graft−DNA) of poly(N-isopropylacrylamide) (PNIPAAm) grafted with single-stranded (ss) DNA were synthesized via radical copolymerization. The bioconjugates self-assembled above its lower critical solution temperature (LCST) in aqueous solution to form micelle-like colloidal nanoparticles. When the ssDNA of the nanoparticle hybridizes with complementary DNA, the particles aggregate above a certain threshold of salt concentration with drastically increased turbidity in solution. 2012-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/44882/1/OOI%20WEI%20YANG.pdf Ooi, Wei Yang (2012) Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | QH1 Natural history (General - Including nature conservation, geographical distribution) Ooi, Wei Yang Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title | Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title_full | Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title_fullStr | Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title_full_unstemmed | Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title_short | Synthesis And Characterization Of Thermoresponsive Poly(N-Isoproylacrylamide)-DNA Bioconjugates |
| title_sort | synthesis and characterization of thermoresponsive poly(n-isoproylacrylamide)-dna bioconjugates |
| topic | QH1 Natural history (General - Including nature conservation, geographical distribution) |
| url | http://eprints.usm.my/44882/1/OOI%20WEI%20YANG.pdf http://eprints.usm.my/44882/ |
| url_provider | http://eprints.usm.my/ |