Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent.
Gemcitabine remains the standard treatment for pancreatic cancer. although most patients acquire resistance to the therapy. Up-regulated in pancreatic cancer. SIRTI is involved in tumorigenesis and drug resistance, However the mechanism through which SIRTl regulates drug sensitivity in cancer cells...
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| Format: | Monograph |
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Universiti Sains Malaysia
2016
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| Online Access: | http://eprints.usm.my/36903/ |
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