Possible Participation of Nitric Oxide/Cyclic Guanosine Monophosphate/Protein Kinase C/ATP-Sensitive K+ Channels Pathway in the Systemic Antinociception of Flavokawin B

The possible mechanisms of action in the antinociceptive activity induced by systemic administration (intraperitoneal, i.p.) of flavokawin B (FKB) were analysed using chemical models of nociception in mice. It was demonstrated that i.p. administration of FKB to the mice at 0.3, 1.0, 3.0 and 10 mg/kg...

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Main Authors:	Azam Shah Mohamad, Muhammad Nadeem Akhtar, Shaik Ibrahim Khalivulla, Enoch Kumar Perimal, Mohamed Hanief Khalid, Hui Ming Ong, Seema Zareen, Ahmad Akira, Daud Ahmad Israf, Nordin Lajis, Mohd Roslan Sulaiman
Format:	journal::journal article
Language:	en_US
Published:	Blackwell Publishing Ltd 2024
Subjects:	NITRIC oxide CYCLIC guanylic acid PROTEIN kinases ADENOSINE triphosphate LABORATORY mice PHORBOLS
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