Pengembungan Hidrogel Selulosa Bakteria-asid Akrilik : Sensitiviti Terhadap Rangsangan Luar
This study evaluated various environmental factors affecting the swelling degree of bacterial cellulose-acrylic acid hydrogels. Aqueous bacterial cellulose-acrylic acid (4:1) mixtures were prepared and subjected to electron beam irradiation at 30 and 50 kGy. Swelling rate under influenced of pH, tem...
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| Main Authors: | , , , , |
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| Format: | journal::journal article |
| Language: | en_US |
| Published: |
Penerbit UKM
2024
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| Subjects: | |
| Online Access: | http://www.ukm.my/jsm/malay_journals/jilid38bil5_2009/Jilid38Bil5_2009_ms785-791.html |
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| Summary: | This study evaluated various environmental factors affecting the swelling degree of bacterial cellulose-acrylic acid hydrogels. Aqueous bacterial cellulose-acrylic acid (4:1) mixtures were prepared and subjected to electron beam irradiation at 30 and 50 kGy. Swelling rate under influenced of pH, temperature and ionic strength was investigated from 1 to 24 hours. Swelling degree of hydrogels was dependent on irradiation dose: those synthesized at 50 kGy exhibited significant higher swelling degree (p<0.0001) in methanol (619%) compared to water (510%) at room temperature after 24 hours. External ionic strength affected swelling, i.e, elevation in sodium chloride concentration decreased swelling degree. Hydrogels were also sensitive to pH: swelling increased with increasing pH and was optimal at pH 7. Swelling also increased with increasing temperature from 25¡C to 50¡C. In conclusion, the ability of electron irradiated bacterial cellulose-acrylic acid hydrogels to respond to various external environment make it a material to be developed as an active delivery system for drugs, proteins and hormones. |
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