BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration

BRF1 is a rate-limiting factor for RNA Polymerase III-mediated transcription and is elevated in numerous cancers. Here, we report that elevated levels of BRF1 associate with poor prognosis in human prostate cancer. In vitro studies in human prostate cancer cell lines demonstrated that transient over...

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Bibliographic Details

Main Authors:	Loveridge, CJ, Slater, S, Campbell, KJ, Nam, NA, Knight, J, Ahmad, I, Hedley, A, Lilla, S, Repiscak, P, Patel, R, Salji, M, Fleming, J, Mitchell, L, Nixon, C, Strathdee, D, Neilson, M, Ntala, C, Bryson, S, Zanivan, S, Edwards, J, Robson, CN, Goodyear, CS, Blyth, K, Leung, HY
Format:	Article
Language:	English en_US
Published:	Nature Publishing Group 2024
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