Cerium oxide nanoparticles: green synthesis and biological applications
CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells....
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| Main Authors: | , , |
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| Format: | Article |
| Language: | en |
| Published: |
Dove Medical Press
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61069/1/Cerium%20oxide%20nanoparticles%20green%20synthesis%20and%20biological%20applications.pdf http://psasir.upm.edu.my/id/eprint/61069/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325136/pdf/ijn-12-1401.pdf |
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| Summary: | CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology. |
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