Intermittent afatinib treatment suppresses the growth of resistant T790M-H1975 cells in non-small cell lung cancer (NSCLC) co-culture

Objectives: Most non-small-cell lung cancers (NSCLC) that harbour an epidermal growth factor receptor (EGFR) mutation are treated with afatinib. Resistance emerges in most patients, making treatment ineffective. Reports suggest intermittent treatment (IT) delays the emergence of resistance compared...

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Main Authors:	Faisal Hamdi, Amir Imran, Poh, Wen Tsin, Lim, Jonathan Chee Woei, Daut, Ummi Nadira, How, Soon Hin, Pang, Yong Kek, Stanslas, Johnson
Format:	Article
Language:	en
Published:	Walter de Gruyter GmbH 2025
Subjects:	Oncology
Online Access:	http://psasir.upm.edu.my/id/eprint/124737/1/124737.pdf http://psasir.upm.edu.my/id/eprint/124737/ https://www.degruyterbrill.com/document/doi/10.1515/oncologie-2025-0178/html
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