A protocol integrating aptamer based magnetic separation and gentle dsDNAse cleavage for exosomes isolation and multi-exosomics analysis

Background: Exosomes, as key mediators of intercellular communication, are increasingly implicated in the pathogenesis of various diseases. Multiomics investigations have uncovered functional roles of low-molecular-weight biomolecules in exosomes. However, conventional methods for isolating exosomes...

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Main Authors:	Sun, Feifei, Jiang, Xiaofei, Shi, Jiachen, Zhang, Yu, Liu, Xiangyang, Liu, Yuanfa, Tan, Chin Ping, Chen, Mingquan, Xu, Yong Jiang
Format:	Article
Language:	en
Published:	Elsevier 2026
Subjects:	Analytical Chemistry Environmental Chemistry
Online Access:	http://psasir.upm.edu.my/id/eprint/122225/1/122225.pdf http://psasir.upm.edu.my/id/eprint/122225/ https://linkinghub.elsevier.com/retrieve/pii/S0003267025012449
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