Optimization of medium formulations for biomass vaccine production of gdhA derivative Pasteurella multocida B:2 using statistical experimental design

The glutamate dehydrogenase (gdhA) gene of a pathogenic Pasteurella multocida B:2 was successfully inactivated to create an attenuated strain as a vaccine candidate against hemorrhagic septicemia (HS) in ruminants. This study presents a novel approach to optimizing the medium formulation for high-th...

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Bibliographic Details

Main Authors:	Oslan, Siti Nur Hazwani, Loo, Jiun Shen, Mohamad, Rosfarizan, Bejo, Siti Khairani, Saad, Mohd Zamri
Format:	Article
Language:	en
Published:	Elsevier 2025
Online Access:	http://psasir.upm.edu.my/id/eprint/115934/1/115934.pdf http://psasir.upm.edu.my/id/eprint/115934/ https://linkinghub.elsevier.com/retrieve/pii/S1878818125000179
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