Effect of domain manipulation in the Staphylococcal Phage endolysin, Endo88, on lytic efficiency and host range
The bacteriophage endolysin Endo88 targeting Staphylococcus aureus PS88 consists of the CHAP and Amidase-2 enzymatic domains and one SH3b targeting domain. In this study, the effects of domain manipulations on Endo88 functionality were determined. Three truncated mutants of Endo88 (CHAP, CHAPAmidase...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Springer
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/113322/1/113322.pdf http://psasir.upm.edu.my/id/eprint/113322/ https://link.springer.com/article/10.1007/s12033-024-01216-4 |
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