A rare occurrence of opportunistic infection by Streptococcus mitis due to antibiotic-induced neutropenia in Prosthetic joint infection
Prosthetic joint infection (PJI) is a devastating complication in arthroplasty surgery. Although the prevalence is less than 2, its functional and financial implications are significant. Part of its treatment involves the usage of prolonged and high-dose systemic antibiotics. Ironically, this predis...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Springer Nature Group
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/106661/ https://www.cureus.com/articles/124330-a-rare-occurrence-of-opportunistic-infection-by-streptococcus-mitis-due-to-antibiotic-induced-neutropenia-in-prosthetic-joint-infection#!/ |
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| Summary: | Prosthetic joint infection (PJI) is a devastating complication in arthroplasty surgery. Although the prevalence is less than 2, its functional and financial implications are significant. Part of its treatment involves the usage of prolonged and high-dose systemic antibiotics. Ironically, this predisposes the patient to unwanted adverse effects caused by the drugs. We report a case of cefazolin-induced neutropenia that led to Streptococcus mitis (S. mitis) bacteraemia in a patient with Staphylococcus aureus PJI. There have been no previous reports on cefazolin-induced neutropenic bacteraemia complicating the treatment of PJI. This case report aims to create awareness among the attending physicians on the possibility of cefazolin-induced neutropenia, which led to bacteraemia from an opportunistic microorganism. The reversal was as simple as cessation of the antibiotic itself. However, if not recognized, it could be fatal. |
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