Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review

To comprehend the complex messages of science, we require visual senses for better understanding. It is evident that our visualisation falls short at minute levels. Surface Enhanced Raman Spectroscopy (SERS) facilitates the temporal identification and characterisation of the molecular composition, s...

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Main Authors: Balasubramani S.R., Nagappan K., Ewe L.S., Viswanathan K., Yew W.K., Thiraviam S.G., Sadana S., Samuel T.K.D., Kamalakannan K.
Other Authors: 59045865900
Format: Review
Published: Taylor and Francis Ltd. 2025
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author Balasubramani S.R.
Nagappan K.
Ewe L.S.
Viswanathan K.
Yew W.K.
Thiraviam S.G.
Sadana S.
Samuel T.K.D.
Kamalakannan K.
author2 59045865900
author_facet 59045865900
Balasubramani S.R.
Nagappan K.
Ewe L.S.
Viswanathan K.
Yew W.K.
Thiraviam S.G.
Sadana S.
Samuel T.K.D.
Kamalakannan K.
author_sort Balasubramani S.R.
building UNITEN Library
collection Institutional Repository
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
continent Asia
country Malaysia
description To comprehend the complex messages of science, we require visual senses for better understanding. It is evident that our visualisation falls short at minute levels. Surface Enhanced Raman Spectroscopy (SERS) facilitates the temporal identification and characterisation of the molecular composition, structure, and dynamics of a given sample. This technology promises to be an effective solution for many undiscovered and unaccounted outcomes in the chemical, biochemical, and clinical fields. Hence, early detection of large panels of bio targets, contaminants, and toxins is assessed with high levels of sensitivity and multiplexity, tracing to the extent of Nano (10?9) levels. Over the past decade, nanomaterials-based SERS has emerged, shedding light on the importance of different dimensions of nanomaterials, primarily in the development of SERS sensing for various applications. SERS Nano probes offer remarkable improvements by focusing and imaging, utilising the Raman scattering efficiency, wherein molecules are absorbed on a nanostructured surface. This article elucidates the SERS principle, classification based on sensing dimensions, and its application in the field of food safety and drug monitoring, detecting various proteins, viruses, and bacteria, both in-vitro and in-vivo imaging, cancer biomarker detection, as well as detecting nutrients, pesticides, and foodborne pathogens by SERS. It serves as a collective review of recent advancements that have flourished in the past few years, highlighting concepts, issues, and challenges with the prior motive of incorporating and stimulating wider interest in developing SERS nanomaterial applications for chemical engineering. ? 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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publisher Taylor and Francis Ltd.
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spelling my.uniten.dspace-371392025-03-03T15:47:54Z Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review Balasubramani S.R. Nagappan K. Ewe L.S. Viswanathan K. Yew W.K. Thiraviam S.G. Sadana S. Samuel T.K.D. Kamalakannan K. 59045865900 59046412800 58032789200 59046412900 57361611300 59046413000 59047514900 59047515000 59265625200 Food safety Light transmission Nanosensors Patient monitoring Probes Raman spectroscopy Viruses Bio-chemical applications Biphotonic Chemical applications Chemical imaging Chemical sensing Clinical application Critical review Molecular compositions Nano probes Surface enhanced Raman spectroscopy Nanostructured materials To comprehend the complex messages of science, we require visual senses for better understanding. It is evident that our visualisation falls short at minute levels. Surface Enhanced Raman Spectroscopy (SERS) facilitates the temporal identification and characterisation of the molecular composition, structure, and dynamics of a given sample. This technology promises to be an effective solution for many undiscovered and unaccounted outcomes in the chemical, biochemical, and clinical fields. Hence, early detection of large panels of bio targets, contaminants, and toxins is assessed with high levels of sensitivity and multiplexity, tracing to the extent of Nano (10?9) levels. Over the past decade, nanomaterials-based SERS has emerged, shedding light on the importance of different dimensions of nanomaterials, primarily in the development of SERS sensing for various applications. SERS Nano probes offer remarkable improvements by focusing and imaging, utilising the Raman scattering efficiency, wherein molecules are absorbed on a nanostructured surface. This article elucidates the SERS principle, classification based on sensing dimensions, and its application in the field of food safety and drug monitoring, detecting various proteins, viruses, and bacteria, both in-vitro and in-vivo imaging, cancer biomarker detection, as well as detecting nutrients, pesticides, and foodborne pathogens by SERS. It serves as a collective review of recent advancements that have flourished in the past few years, highlighting concepts, issues, and challenges with the prior motive of incorporating and stimulating wider interest in developing SERS nanomaterial applications for chemical engineering. ? 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Article in press 2025-03-03T07:47:54Z 2025-03-03T07:47:54Z 2024 Review 10.1080/03067319.2024.2339453 2-s2.0-85192271122 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192271122&doi=10.1080%2f03067319.2024.2339453&partnerID=40&md5=19e1165f58283f56cab78f09bbb2bfae https://irepository.uniten.edu.my/handle/123456789/37139 All Open Access; Hybrid Gold Open Access Taylor and Francis Ltd. Scopus
spellingShingle Food safety
Light transmission
Nanosensors
Patient monitoring
Probes
Raman spectroscopy
Viruses
Bio-chemical applications
Biphotonic
Chemical applications
Chemical imaging
Chemical sensing
Clinical application
Critical review
Molecular compositions
Nano probes
Surface enhanced Raman spectroscopy
Nanostructured materials
Balasubramani S.R.
Nagappan K.
Ewe L.S.
Viswanathan K.
Yew W.K.
Thiraviam S.G.
Sadana S.
Samuel T.K.D.
Kamalakannan K.
Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title_full Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title_fullStr Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title_full_unstemmed Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title_short Recent developments in surface-enhanced Raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
title_sort recent developments in surface-enhanced raman spectroscopy in the field of chemical, biochemical and clinical application? a critical review
topic Food safety
Light transmission
Nanosensors
Patient monitoring
Probes
Raman spectroscopy
Viruses
Bio-chemical applications
Biphotonic
Chemical applications
Chemical imaging
Chemical sensing
Clinical application
Critical review
Molecular compositions
Nano probes
Surface enhanced Raman spectroscopy
Nanostructured materials
url_provider http://dspace.uniten.edu.my/