CA19-9 and CEA biosensors in pancreatic cancer
Cancer is a complex pathophysiological condition causing millions of deaths each year. Early diagnosis is essential especially for pancreatic cancer. Existing diagnostic tools rely on circulating biomarkers such as Carbohydrate Antigen 19?9 (CA19-9) and Carcinoembryonic Antigen (CEA). Unfortunately,...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Review |
| Published: |
Elsevier B.V.
2025
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1833413285088591872 |
|---|---|
| author | Ahmadipour M. Bhattacharya A. Sarafbidabad M. Syuhada Sazali E. Krishna Ghoshal S. Satgunam M. Singh R. Rezaei Ardani M. Missaoui N. Kahri H. Pal U. Ling Pang A. |
| author2 | 55533484700 |
| author_facet | 55533484700 Ahmadipour M. Bhattacharya A. Sarafbidabad M. Syuhada Sazali E. Krishna Ghoshal S. Satgunam M. Singh R. Rezaei Ardani M. Missaoui N. Kahri H. Pal U. Ling Pang A. |
| author_sort | Ahmadipour M. |
| building | UNITEN Library |
| collection | Institutional Repository |
| content_provider | Universiti Tenaga Nasional |
| content_source | UNITEN Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Cancer is a complex pathophysiological condition causing millions of deaths each year. Early diagnosis is essential especially for pancreatic cancer. Existing diagnostic tools rely on circulating biomarkers such as Carbohydrate Antigen 19?9 (CA19-9) and Carcinoembryonic Antigen (CEA). Unfortunately, these markers are nonspecific and may be increased in a variety of disorders. Accordingly, diagnosis of pancreatic cancer generally involves more invasive approaches such as biopsy as well as imaging studies. Recent advances in biosensor technology have allowed the development of precise diagnostic tools having enhanced analytical sensitivity and specificity. Herein we examine these advances in the detection of cancer in general and in pancreatic cancer specifically. Furthermore, we highlight novel technologies in the measurement of CA19-9 and CEA and explore their future application in the early detection of pancreatic cancer. ? 2024 Elsevier B.V. |
| format | Review |
| id | my.uniten.dspace-36866 |
| institution | Universiti Tenaga Nasional |
| publishDate | 2025 |
| publisher | Elsevier B.V. |
| record_format | dspace |
| spelling | my.uniten.dspace-368662025-03-03T15:45:19Z CA19-9 and CEA biosensors in pancreatic cancer Ahmadipour M. Bhattacharya A. Sarafbidabad M. Syuhada Sazali E. Krishna Ghoshal S. Satgunam M. Singh R. Rezaei Ardani M. Missaoui N. Kahri H. Pal U. Ling Pang A. 55533484700 57203499788 56486136100 58852080700 57202443208 48561725600 57221127160 57221374739 57212210643 57191823566 8908351700 58852624900 Biomarkers, Tumor CA-19-9 Antigen Carcinoembryonic Antigen Humans Pancreatic Neoplasms Sensitivity and Specificity CA 19-9 antigen carbon carbon nanotube carcinoembryonic antigen fullerene derivative graphene metal organic framework metal oxide nanomaterial transition element tumor marker CA 19-9 antigen carcinoembryonic antigen tumor marker antigen detection biological trait biotechnology cancer mortality carcinogenesis classification diagnostic imaging early cancer diagnosis electrochemical analysis ellipsometry human invasive procedure nonhuman pancreas biopsy pancreas cancer pathophysiology point of care testing Raman spectrometry Review sensitivity and specificity surface plasmon resonance tumor biopsy pancreas tumor Cancer is a complex pathophysiological condition causing millions of deaths each year. Early diagnosis is essential especially for pancreatic cancer. Existing diagnostic tools rely on circulating biomarkers such as Carbohydrate Antigen 19?9 (CA19-9) and Carcinoembryonic Antigen (CEA). Unfortunately, these markers are nonspecific and may be increased in a variety of disorders. Accordingly, diagnosis of pancreatic cancer generally involves more invasive approaches such as biopsy as well as imaging studies. Recent advances in biosensor technology have allowed the development of precise diagnostic tools having enhanced analytical sensitivity and specificity. Herein we examine these advances in the detection of cancer in general and in pancreatic cancer specifically. Furthermore, we highlight novel technologies in the measurement of CA19-9 and CEA and explore their future application in the early detection of pancreatic cancer. ? 2024 Elsevier B.V. Final 2025-03-03T07:45:19Z 2025-03-03T07:45:19Z 2024 Review 10.1016/j.cca.2024.117788 2-s2.0-85183542232 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85183542232&doi=10.1016%2fj.cca.2024.117788&partnerID=40&md5=3904274197fc3f069667d4269bb87526 https://irepository.uniten.edu.my/handle/123456789/36866 554 117788 Elsevier B.V. Scopus |
| spellingShingle | Biomarkers, Tumor CA-19-9 Antigen Carcinoembryonic Antigen Humans Pancreatic Neoplasms Sensitivity and Specificity CA 19-9 antigen carbon carbon nanotube carcinoembryonic antigen fullerene derivative graphene metal organic framework metal oxide nanomaterial transition element tumor marker CA 19-9 antigen carcinoembryonic antigen tumor marker antigen detection biological trait biotechnology cancer mortality carcinogenesis classification diagnostic imaging early cancer diagnosis electrochemical analysis ellipsometry human invasive procedure nonhuman pancreas biopsy pancreas cancer pathophysiology point of care testing Raman spectrometry Review sensitivity and specificity surface plasmon resonance tumor biopsy pancreas tumor Ahmadipour M. Bhattacharya A. Sarafbidabad M. Syuhada Sazali E. Krishna Ghoshal S. Satgunam M. Singh R. Rezaei Ardani M. Missaoui N. Kahri H. Pal U. Ling Pang A. CA19-9 and CEA biosensors in pancreatic cancer |
| title | CA19-9 and CEA biosensors in pancreatic cancer |
| title_full | CA19-9 and CEA biosensors in pancreatic cancer |
| title_fullStr | CA19-9 and CEA biosensors in pancreatic cancer |
| title_full_unstemmed | CA19-9 and CEA biosensors in pancreatic cancer |
| title_short | CA19-9 and CEA biosensors in pancreatic cancer |
| title_sort | ca19-9 and cea biosensors in pancreatic cancer |
| topic | Biomarkers, Tumor CA-19-9 Antigen Carcinoembryonic Antigen Humans Pancreatic Neoplasms Sensitivity and Specificity CA 19-9 antigen carbon carbon nanotube carcinoembryonic antigen fullerene derivative graphene metal organic framework metal oxide nanomaterial transition element tumor marker CA 19-9 antigen carcinoembryonic antigen tumor marker antigen detection biological trait biotechnology cancer mortality carcinogenesis classification diagnostic imaging early cancer diagnosis electrochemical analysis ellipsometry human invasive procedure nonhuman pancreas biopsy pancreas cancer pathophysiology point of care testing Raman spectrometry Review sensitivity and specificity surface plasmon resonance tumor biopsy pancreas tumor |
| url_provider | http://dspace.uniten.edu.my/ |