Chalcone as a versatile scaffold: An overview
Chalcone is a stable organic compound with an aromatic ring structure and α, β-unsaturated carbonyl moiety. It has a wide spectrum of bioactivities, including anti-HIV, antimicrobial, anticancer, antivirus, antitubercular, antioxidant, and antidiabetes properties. Chalcone derivatives are easily syn...
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| Language: | en |
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Elsevier Inc.
2026
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| Online Access: | http://ir.unimas.my/id/eprint/51144/1/Chalcones%20and%20their%20Derivatives%20Chapter%20in%20book%20ZN.pdf http://ir.unimas.my/id/eprint/51144/ https://www.sciencedirect.com/science/chapter/edited-volume/abs/pii/B9780443301223000248 https://doi.org/10.1016/B978-0-443-30122-3.00024-8 |
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| _version_ | 1854094205676158976 |
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| author | Saba, Farooq Zainab, Ngaini |
| author2 | Mohmmad Younus, Wani |
| author_facet | Mohmmad Younus, Wani Saba, Farooq Zainab, Ngaini |
| author_sort | Saba, Farooq |
| building | Centre for Academic Information Services (CAIS) |
| collection | Institutional Repository |
| content_provider | Universiti Malaysia Sarawak |
| content_source | UNIMAS Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Chalcone is a stable organic compound with an aromatic ring structure and α, β-unsaturated carbonyl moiety. It has a wide spectrum of bioactivities, including anti-HIV, antimicrobial, anticancer, antivirus, antitubercular, antioxidant, and antidiabetes properties. Chalcone derivatives are easily synthesized and have numerous applications in the pharmaceutical industry, liquid crystal sectors, dye-sensitized solar cell sectors, agricultural, cosmetic properties, corrosion inhibition, and many others. Chalcone can be synthesized in many ways, and researchers have been particularly interested in the Claisen–Schmidt condensation process because of its simple conditions and stable reactants. This chapter will cover a brief history of chalcone and its structural features, synthesis, and structural activity relationship of chalcones as active scaffolds for heterocyclic compounds with economical, eco-friendly, effective, and high-yield strategies. |
| format | Book Chapter |
| id | my.unimas.ir-51144 |
| institution | Universiti Malaysia Sarawak |
| language | en |
| publishDate | 2026 |
| publisher | Elsevier Inc. |
| record_format | eprints |
| spelling | my.unimas.ir-511442025-12-31T00:14:21Z http://ir.unimas.my/id/eprint/51144/ Chalcone as a versatile scaffold: An overview Saba, Farooq Zainab, Ngaini QD Chemistry Chalcone is a stable organic compound with an aromatic ring structure and α, β-unsaturated carbonyl moiety. It has a wide spectrum of bioactivities, including anti-HIV, antimicrobial, anticancer, antivirus, antitubercular, antioxidant, and antidiabetes properties. Chalcone derivatives are easily synthesized and have numerous applications in the pharmaceutical industry, liquid crystal sectors, dye-sensitized solar cell sectors, agricultural, cosmetic properties, corrosion inhibition, and many others. Chalcone can be synthesized in many ways, and researchers have been particularly interested in the Claisen–Schmidt condensation process because of its simple conditions and stable reactants. This chapter will cover a brief history of chalcone and its structural features, synthesis, and structural activity relationship of chalcones as active scaffolds for heterocyclic compounds with economical, eco-friendly, effective, and high-yield strategies. Elsevier Inc. Mohmmad Younus, Wani Salman Ahmad, Khan Hao, Shao Anish, Khan 2026 Book Chapter PeerReviewed text en http://ir.unimas.my/id/eprint/51144/1/Chalcones%20and%20their%20Derivatives%20Chapter%20in%20book%20ZN.pdf Saba, Farooq and Zainab, Ngaini (2026) Chalcone as a versatile scaffold: An overview. In: Chalcones and their Derivatives From Synthesis to Applications. Elsevier Inc., Amsterdam, Netherlands, pp. 1-18. ISBN 978-0-443-30122-3 https://www.sciencedirect.com/science/chapter/edited-volume/abs/pii/B9780443301223000248 https://doi.org/10.1016/B978-0-443-30122-3.00024-8 |
| spellingShingle | QD Chemistry Saba, Farooq Zainab, Ngaini Chalcone as a versatile scaffold: An overview |
| title | Chalcone as a versatile scaffold: An overview |
| title_full | Chalcone as a versatile scaffold: An overview |
| title_fullStr | Chalcone as a versatile scaffold: An overview |
| title_full_unstemmed | Chalcone as a versatile scaffold: An overview |
| title_short | Chalcone as a versatile scaffold: An overview |
| title_sort | chalcone as a versatile scaffold: an overview |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/51144/1/Chalcones%20and%20their%20Derivatives%20Chapter%20in%20book%20ZN.pdf http://ir.unimas.my/id/eprint/51144/ https://www.sciencedirect.com/science/chapter/edited-volume/abs/pii/B9780443301223000248 https://doi.org/10.1016/B978-0-443-30122-3.00024-8 |
| url_provider | http://ir.unimas.my/ |