Functional Outcomes of Inpatient Prehabilitation for Pseudomyxoma Peritonei: A Case Report

Introduction : Pseudomyxoma peritonei (PMP) is a rare but debilitating abdominal cancer that can cause significant functional limitations and quality of life. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are the standard treatments for PMP. Prehabilitation is...

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Main Authors: Chung Khian, Yew, Chiann Ni, Thiam, Heng Jee, See, Nor Hanan, Nasir, Muhammad Zafril Izhar, MZ, Siti Nur Aida, Zailan, Nur Syafariza, Izmin, Chau Chung, Chai
Format: Article
Language:en
Published: Clinical Research Centre Hospital Raja Permaisuri Bainun 2025
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Online Access:http://ir.unimas.my/id/eprint/50526/3/PMJ%20vol.5%20supp.1%202025%20-%20Copy.pdf
http://ir.unimas.my/id/eprint/50526/
https://mysitasi.mohe.gov.my/journal-website/journal/e-PMJ/?pathId=aeb72169-df12-4b5b-81a7-161d9fc5da30
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Summary:Introduction : Pseudomyxoma peritonei (PMP) is a rare but debilitating abdominal cancer that can cause significant functional limitations and quality of life. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are the standard treatments for PMP. Prehabilitation is a novel approach to optimize the physical and psychological status of patients prior to cancer treatment. This case report aims to evaluate the functional outcome of a two-week inpatient prehabilitation for a 47 years old, Malay lady with PMP secondary to mucinous neoplasm planning for CRS and HIPEC using standardized measures of health-related quality of life and functional capacity. Report: The 36-item Short Form Health Survey (SF-36) is a measure of health-related quality of life. The prehabilitation program shows a positive impact on most of the measured domains, especially “role limitations due to emotional problems”. This significant improvement from 66.7% to 100% after prehabilitation indicates that the patient no longer has role limitations due to emotional issues. These results indicate that prehabilitation can improve the physical and emotional readiness of individuals before they undergo a surgical procedure, leading to better outcomes. The patient’s 6-minute walking distance improved from 194 meters at admission to 404 meters at discharge, indicating a better functional capacity in walking endurance and aerobic capacity. Conclusion: This case report provides preliminary evidence of the effectiveness of inpatient prehabilitation. The patient showed improvements in health-related quality of life and physical function after prehabilitation program prior to surgery. Further research is needed to evaluate the effectiveness of prehabilitation in larger populations of PMP patients planning for CRS and HIPEC.