Neurobiology of chronic caffeine use and withdrawal : Mechanisms, effects and implications

Caffeine is the most widely consumed psychoactive substance worldwide and is increasingly being explored for its potential pharmacological applications, including in neurodegenerative diseases, cognitive enhancement, and pain modulation. However, chronic caffeine use leads to neuroadaptive changes t...

Full description

Bibliographic Details

Main Authors:	Yu Zhao, Lee, Ker Ni, Chua, Fui Ling, Voon, Chau Ling, Tham, Yu Cheng, Ho, Ming Tatt, Lee
Format:	Article
Language:	en
Published:	Elsevier Ltd. 2026
Subjects:	BF Psychology QP Physiology RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RM Therapeutics. Pharmacology
Online Access:	http://ir.unimas.my/id/eprint/50077/3/Neurobiology%20of%20chronic%20caffeine%20-%20Copy.pdf http://ir.unimas.my/id/eprint/50077/ https://www.sciencedirect.com/science/article/pii/S027869152500585X https://doi.org/10.1016/j.fct.2025.115817
Tags:	Add Tag No Tags, Be the first to tag this record!