Synthesis of molecularly imprinted polymers of vanillic acid and extraction of vanillic acid from spiked blood serum

Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a phenolic acid found in many plant extracts. It is used as a flavoring and scent agent and produces a pleasant, creamy odor. It is widely used in many applications for therapeutic purposes to flavoring agent. Molecularly imprinted polymers of van...

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Main Authors: Showkat Ahmad, Bhawani, Salma, Bakhtiar, Rachel Marcella, Roland, Syed Rizwan, Shafqat, Mohamad Nasir, Mohamad Ibrahim
Format: Article
Language:en
Published: Open Science Publishers 2020
Subjects:
Online Access:http://ir.unimas.my/id/eprint/48659/1/Synthesis%20of%20molecularly.pdf
http://ir.unimas.my/id/eprint/48659/
https://japsonline.com/abstract.php?article_id=3113&sts=2
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Summary:Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a phenolic acid found in many plant extracts. It is used as a flavoring and scent agent and produces a pleasant, creamy odor. It is widely used in many applications for therapeutic purposes to flavoring agent. Molecularly imprinted polymers of vanillic acid were synthesized by precipitation polymerization with a noncovalent approach for the extraction from blood serum. Three different imprinted polymers have been synthesized with varying molar ratio of monomer. The synthesized polymer particles were characterized using Fourier-transform infrared spectroscopy and scanning electron microscopy. The extraction efficiency of highly selected imprinted polymer of vanillic acid from spiked blood serum was about 80%.