Pharmacophore modelling of vanillin derivatives, favipiravir, chloroquine, hydroxychloroquine, monolaurin and tetrodotoxin as MPro inhibitors of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

Objectives: The aim of this study was to use Ligand-based pharmacophore modelling approach for four established antiviral drugs, namely remdesivir, lopinavir, ritonavir and hydroxychloroquine for COVID-19 inhibitors as training sets. In this study Twenty vanillin derivatives together with monolaur...

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Bibliographic Details

Main Authors:	Law, Woon Yi, Mohd Razip, Asaruddin, Showkat, Ahmad Bhawani, Samsur, Mohamad
Format:	Article
Language:	en
Published:	BioMed Central Ltd 2020
Subjects:	QD Chemistry
Online Access:	http://ir.unimas.my/id/eprint/45384/1/Pharmacophore.pdf http://ir.unimas.my/id/eprint/45384/ https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-020-05379-6 https://doi.org/10.1186/s13104-020-05379-6
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