Phytochemical studies and biological activities of smilax myosotilora
Phytochemical studies have been carried out on the Smilax myosotiflora, which is commonly known as 'ubi jaga' in Malaysia, from the family Smilacaceae. Most of the phytochemical surveys carried out in this family were concentrated with sterol compounds. Besides that, other compounds pres...
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| Main Author: | |
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| Format: | Final Year Project Report / IMRAD |
| Language: | en |
| Published: |
Universiti Malaysia Sarawak, (UNIMAS)
2014
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/34087/1/Racheal%20%20ft.pdf http://ir.unimas.my/id/eprint/34087/ |
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| Summary: | Phytochemical studies have been carried out on the Smilax myosotiflora, which is commonly known as 'ubi
jaga' in Malaysia, from the family Smilacaceae. Most of the phytochemical surveys carried out in this family
were concentrated with sterol compounds. Besides that, other compounds present in the plant have been
studies as well. The MeOH crude extract obtained is about 10.88g. Isolation was carried out using various
chromatographic techniques. Compound isolated and purified using Thin layer Chromatography (TLC),
Preparative thin layer chromatography (PTLC) and Column Chromatography (CC) technique. The pure
compound was isolated namely /3-sitosterol. This structure compound were elucidated and characterized by
spectroscopic analysis using 'H and ''C Nuclear Magnetic Resonance (NMR) Spectroscopy, Fourier
Transform Infrared Spectroscopy (FTIR), and CHN Elemental Analyzer. Biological evaluations were carried
out on the fractions and crude extracts. The results stated that the compound 1 has higher LC;) value that
was 210.0 ppm. This higher value indicated that compound 1 has less toxicity against Artemia salina. The
fraction 1 that has a compound 1 was the highest percentage of activity scanvenging among the entire
fraction which is 93.15 %. |
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