Electrochemical Determination of Japanese Encephalitis Virus Antigen Using Silver Nanoparticles Modified Screen-Printed Carbon Electrode
In this study, we aim to fabricate a silver nanoparticles (Ag NPs) based electrochemical biosensor for Japanese Encephalitis virus antigen detection. Ag NPs were deposited onto screen-printed carbon electrode (SPCE) and the electrochemical properties of the Ag NPs modified SPCE were investigated...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Host
2019
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/31391/1/Electrochemical%20Determination%20of%20Japanese%20Encephalitis%20Virus%20Antigen%20Using%20Silver%20Nanoparticles%20Modified%20Screen-Printed%20Carbon%20Electrode.pdf http://ir.unimas.my/id/eprint/31391/ http://nanobe.org/Data/View/619 |
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| Summary: | In this study, we aim to fabricate a silver nanoparticles (Ag NPs) based electrochemical biosensor
for Japanese Encephalitis virus antigen detection. Ag NPs were deposited onto screen-printed carbon
electrode (SPCE) and the electrochemical properties of the Ag NPs modified SPCE were investigated
via electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). It was observed
that the deposition of Ag NPs onto electrode surface has significantly enhanced the conductivity up to
20.5% than that of bare SPCE. The EIS data indicated limit of detection (LOD) of 2.60 ng/mL (at S/
N = 3) towards JEV antigen, with an analysis assay time of 20 min. This presented Ag NPs modified
SPCE has demonstrated a promising and rapid alternative to conventional biosensing techniques
towards JEV antigen. |
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