Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network
The Diabetic Retinopathy Clinical Research Network (DRCR.net) performs studies on new treatments for diabetic retinopathy. This review aims to summarise recent findings from DRCR.net studies on the treatment of diabetic macular oedema. We performed a PubMed search of articles from the DRCR.net, whic...
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| Language: | en |
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Singapore Medical Association
2015
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| Online Access: | http://ir.unimas.my/id/eprint/22011/1/Advances.pdf http://ir.unimas.my/id/eprint/22011/ https://www.ncbi.nlm.nih.gov/pubmed/26034315 |
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| author | Lim, Lik Thai Chia, Seen Nee Yann, Elliott Ah-Kee Chew, Nejia Gupta, Manish |
| author_facet | Lim, Lik Thai Chia, Seen Nee Yann, Elliott Ah-Kee Chew, Nejia Gupta, Manish |
| author_sort | Lim, Lik Thai |
| building | Centre for Academic Information Services (CAIS) |
| collection | Institutional Repository |
| content_provider | Universiti Malaysia Sarawak |
| content_source | UNIMAS Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | The Diabetic Retinopathy Clinical Research Network (DRCR.net) performs studies on new treatments for diabetic retinopathy. This review aims to summarise recent findings from DRCR.net studies on the treatment of diabetic macular oedema. We performed a PubMed search of articles from the DRCR.net, which included all studies pertaining to the treatment of diabetic maculopathy. The main outcome measures were retinal thickening as assessed by central subfield thickness on optical coherence tomography and improvement of visual acuity on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Findings from each study were divided into modalities of treatment, namely photocoagulation, bevacizumab, triamcinolone, ranibizumab and vitrectomy. While modified ETDRS focal/grid laser remains the standard of care, intravitreal corticosteroids or anti-vascular endothelial growth factor agents have also proven to be effective, although they come with associated side effects. The choice of treatment modality for diabetic macular oedema is a clinical judgement call, and depends on the patient’s clinical history and assessment. |
| format | Article |
| id | my.unimas.ir-22011 |
| institution | Universiti Malaysia Sarawak |
| language | en |
| publishDate | 2015 |
| publisher | Singapore Medical Association |
| record_format | eprints |
| spelling | my.unimas.ir-220112022-01-28T01:24:48Z http://ir.unimas.my/id/eprint/22011/ Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network Lim, Lik Thai Chia, Seen Nee Yann, Elliott Ah-Kee Chew, Nejia Gupta, Manish R Medicine (General) RE Ophthalmology The Diabetic Retinopathy Clinical Research Network (DRCR.net) performs studies on new treatments for diabetic retinopathy. This review aims to summarise recent findings from DRCR.net studies on the treatment of diabetic macular oedema. We performed a PubMed search of articles from the DRCR.net, which included all studies pertaining to the treatment of diabetic maculopathy. The main outcome measures were retinal thickening as assessed by central subfield thickness on optical coherence tomography and improvement of visual acuity on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Findings from each study were divided into modalities of treatment, namely photocoagulation, bevacizumab, triamcinolone, ranibizumab and vitrectomy. While modified ETDRS focal/grid laser remains the standard of care, intravitreal corticosteroids or anti-vascular endothelial growth factor agents have also proven to be effective, although they come with associated side effects. The choice of treatment modality for diabetic macular oedema is a clinical judgement call, and depends on the patient’s clinical history and assessment. Singapore Medical Association 2015 Article PeerReviewed text en http://ir.unimas.my/id/eprint/22011/1/Advances.pdf Lim, Lik Thai and Chia, Seen Nee and Yann, Elliott Ah-Kee and Chew, Nejia and Gupta, Manish (2015) Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network. Singapore Medical Journal, 56 (5). pp. 237-247. ISSN 0037-5675 https://www.ncbi.nlm.nih.gov/pubmed/26034315 DOI: 10.11622/smedj.2015071 |
| spellingShingle | R Medicine (General) RE Ophthalmology Lim, Lik Thai Chia, Seen Nee Yann, Elliott Ah-Kee Chew, Nejia Gupta, Manish Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title | Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title_full | Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title_fullStr | Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title_full_unstemmed | Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title_short | Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network |
| title_sort | advances in the management of diabetic macular oedema based on evidence from the diabetic retinopathy clinical research network |
| topic | R Medicine (General) RE Ophthalmology |
| url | http://ir.unimas.my/id/eprint/22011/1/Advances.pdf http://ir.unimas.my/id/eprint/22011/ https://www.ncbi.nlm.nih.gov/pubmed/26034315 |
| url_provider | http://ir.unimas.my/ |