Chromenone-based GSK-3ß inhibitors as potential therapeutic targets for cardiovascular diseases: In silico study, molecular dynamics, and ADMET profiles

Glycogen synthase kinase-3 beta (GSK-3ß) regulates glycogen metabolism and many different cellulars, including apoptosis, signaling, and neural. It is a crucial therapeutic receptor in heart disease, type 2 diabetes, and Alzheimer’s. In this study, using computational methods, flavonoid compounds we...

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Main Authors:	Min Zhang, San Zhou, Noor H. Obaid, Usama S. Altimari, Mohanad Adel Mohammed, Ahmed Kareem Obaid Aldulaim, Emad Salaam Abood, Hossam Kotb, Ayesheh Enayati, Vahid Khori, Hassan Mirzaei, Aref Salehi, Alireza Soltani, Mohd Sani Sarjadi, Md. Lutfor Rahman
Format:	Article
Language:	en en
Published:	Elsevier B.V. 2022
Subjects:	QD1-999 Chemistry R5-920 Medicine (General)
Online Access:	https://eprints.ums.edu.my/id/eprint/35099/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/35099/2/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/35099/ https://www.sciencedirect.com/science/article/pii/S1878535222006049 https://doi.org/10.1016/j.arabjc.2022.104288
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