The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis
Noncommunicable diseases such as diabetes are strongly associated with the insulin resistance (IR) status of an individual. However, the prevalence of insulin resistance in Southeast Asia is poorly reported. Hence, this study investigated the prevalence of IR in Southeast Asia from the year 2016 to...
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Multidisciplinary Digital Publishing Institute
2022
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| Online Access: | https://eprints.ums.edu.my/id/eprint/34111/1/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20An%20updated%20systematic%20review%20and%20meta-analysis.ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34111/2/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20an%20updated%20systematic%20review%20and%20meta-analysis.pdf https://eprints.ums.edu.my/id/eprint/34111/ https://www.mdpi.com/1648-9144/58/6/826/htm https://doi.org/10.3390/ medicina58060826 |
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| author | Lucky Poh Wah Goh Suraya Abdul Sani Mohd Khalizan Sabullah Jualang Azlan Gansau |
| author_facet | Lucky Poh Wah Goh Suraya Abdul Sani Mohd Khalizan Sabullah Jualang Azlan Gansau |
| author_sort | Lucky Poh Wah Goh |
| building | UMS Library |
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| content_provider | Universiti Malaysia Sabah |
| content_source | UMS Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Noncommunicable diseases such as diabetes are strongly associated with the insulin resistance (IR) status of an individual. However, the prevalence of insulin resistance in Southeast Asia is poorly reported. Hence, this study investigated the prevalence of IR in Southeast Asia from the year 2016 to 2021. This study was carried out according to PRISMA guidelines. The literature search was conducted utilizing the PubMed and SCOPUS databases from the year 2016 to 2021 using the keywords ‘(insulin AND resistance) OR (insulin AND sensitivity) OR (prevalence OR incidence) AND (Malaysia OR Thailand OR Singapore OR Brunei OR Cambodia OR Indonesia OR Laos OR Myanmar OR Philippines OR Timor leste OR Vietnam)’. Funnel plot and publication bias were assessed using Egger’s tests. Data were expressed as the prevalence rate. Results: A total of 12 studies with 2198 subjects were considered in the meta-analysis. Significant heterogeneity (I2 > 94% and p-value < 0.001) was observed in the meta-analysis. The overall prevalence of IR in Southeast Asia was 44.3%, with Malaysia having the highest prevalence rate at 50.4%, followed by Indonesia at 44.2%. Bias was detected in the meta-analysis. It may be that reports published before the year 2016 met the study selection criteria, but were excluded from the meta-analysis. The results from the meta-analysis indicate that the prevalence of IR in Southeast Asia is very high. This provided insights for healthcare policy makers and public health officials in designing IR screening programs. |
| format | Article |
| id | my.ums.eprints-34111 |
| institution | Universiti Malaysia Sabah |
| language | en en |
| publishDate | 2022 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | eprints |
| spelling | my.ums.eprints-341112022-09-15T07:01:23Z https://eprints.ums.edu.my/id/eprint/34111/ The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis Lucky Poh Wah Goh Suraya Abdul Sani Mohd Khalizan Sabullah Jualang Azlan Gansau RC648-665 Diseases of the endocrine glands. Clinical endocrinology Noncommunicable diseases such as diabetes are strongly associated with the insulin resistance (IR) status of an individual. However, the prevalence of insulin resistance in Southeast Asia is poorly reported. Hence, this study investigated the prevalence of IR in Southeast Asia from the year 2016 to 2021. This study was carried out according to PRISMA guidelines. The literature search was conducted utilizing the PubMed and SCOPUS databases from the year 2016 to 2021 using the keywords ‘(insulin AND resistance) OR (insulin AND sensitivity) OR (prevalence OR incidence) AND (Malaysia OR Thailand OR Singapore OR Brunei OR Cambodia OR Indonesia OR Laos OR Myanmar OR Philippines OR Timor leste OR Vietnam)’. Funnel plot and publication bias were assessed using Egger’s tests. Data were expressed as the prevalence rate. Results: A total of 12 studies with 2198 subjects were considered in the meta-analysis. Significant heterogeneity (I2 > 94% and p-value < 0.001) was observed in the meta-analysis. The overall prevalence of IR in Southeast Asia was 44.3%, with Malaysia having the highest prevalence rate at 50.4%, followed by Indonesia at 44.2%. Bias was detected in the meta-analysis. It may be that reports published before the year 2016 met the study selection criteria, but were excluded from the meta-analysis. The results from the meta-analysis indicate that the prevalence of IR in Southeast Asia is very high. This provided insights for healthcare policy makers and public health officials in designing IR screening programs. Multidisciplinary Digital Publishing Institute 2022-06-19 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34111/1/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20An%20updated%20systematic%20review%20and%20meta-analysis.ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/34111/2/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20an%20updated%20systematic%20review%20and%20meta-analysis.pdf Lucky Poh Wah Goh and Suraya Abdul Sani and Mohd Khalizan Sabullah and Jualang Azlan Gansau (2022) The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis. Medicina, 58. pp. 1-9. https://www.mdpi.com/1648-9144/58/6/826/htm https://doi.org/10.3390/ medicina58060826 https://doi.org/10.3390/ medicina58060826 |
| spellingShingle | RC648-665 Diseases of the endocrine glands. Clinical endocrinology Lucky Poh Wah Goh Suraya Abdul Sani Mohd Khalizan Sabullah Jualang Azlan Gansau The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title | The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title_full | The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title_fullStr | The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title_full_unstemmed | The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title_short | The prevalence of insulin resistance in Malaysia and Indonesia: an updated systematic review and meta-analysis |
| title_sort | prevalence of insulin resistance in malaysia and indonesia: an updated systematic review and meta-analysis |
| topic | RC648-665 Diseases of the endocrine glands. Clinical endocrinology |
| url | https://eprints.ums.edu.my/id/eprint/34111/1/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20An%20updated%20systematic%20review%20and%20meta-analysis.ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34111/2/The%20prevalence%20of%20insulin%20resistance%20in%20Malaysia%20and%20Indonesia%2C%20an%20updated%20systematic%20review%20and%20meta-analysis.pdf https://eprints.ums.edu.my/id/eprint/34111/ https://www.mdpi.com/1648-9144/58/6/826/htm https://doi.org/10.3390/ medicina58060826 https://doi.org/10.3390/ medicina58060826 |
| url_provider | http://eprints.ums.edu.my/ |