N-Alkylation Of 6,6’-Dibromoisoindigo via Tosylate: An Economical Pathway
This paper introduces a substantial and price reasonable pathway to N-alkylate the 6,6’- dibromoisoindigo. The conventional method for this N-alkylation involves the usage of alkyl bromides, which are available in the commercial with high-priced and limited amount. In this research, the price to pur...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | en |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/24098/1/N-Alkylation%20Of%206%2C6%E2%80%99-Dibromoisoindigo%20via%20Tosylate%20An%20Economical%20Pathway.pdf https://eprints.ums.edu.my/id/eprint/24098/ |
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| Summary: | This paper introduces a substantial and price reasonable pathway to N-alkylate the 6,6’- dibromoisoindigo. The conventional method for this N-alkylation involves the usage of alkyl bromides, which are available in the commercial with high-priced and limited amount. In this research, the price to purchase 7-(bromomethyl) pentadecane is four-fold than the cost to synthesize the relevant tosylate from 2-hexyl-1-decanol. The most suitable reaction condition to N-alkylate this 6,6’-dibromoisoindigo is by refluxing it with potassium carbonate in dried DMF under nitrogen atmosphere. After characterization, it can be concluded that 6,6’-dibromoisoindigo has been successfully N-alkylated with tosylate without involved the expensive alkyl bromide. |
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