Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones
Optically active (−)-ephedrine, (−)-norephedrine, and (−)-prolinol were immobilized onto cubicmesoporousMCM-48 silica. The immobilized amino alcohols served as a heterogeneous chiral catalyst for the asymmetric addition of diethylzinc to aldehydes and transfer hydrogenation to ketones. The developed...
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| Online Access: | http://umpir.ump.edu.my/id/eprint/8176/1/Sha_JNM-3.pdf http://umpir.ump.edu.my/id/eprint/8176/ |
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| author | Sarkar, Shaheen M. Md. Eaqub, Ali Lutfor, M. R. M. M., Yusoff |
| author_facet | Sarkar, Shaheen M. Md. Eaqub, Ali Lutfor, M. R. M. M., Yusoff |
| author_sort | Sarkar, Shaheen M. |
| building | UMPSA Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaysia Pahang Al-Sultan Abdullah |
| content_source | UMPSA Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Optically active (−)-ephedrine, (−)-norephedrine, and (−)-prolinol were immobilized onto cubicmesoporousMCM-48 silica. The immobilized amino alcohols served as a heterogeneous chiral catalyst for the asymmetric addition of diethylzinc to aldehydes and transfer hydrogenation to ketones. The developed catalytic process yielded optically enriches secondary aromatic alcohols with 92–99% conversion and 70–82% enantioselectivity. |
| format | Article |
| id | my.ump.umpir.8176 |
| institution | Universiti Malaysia Pahang |
| language | en |
| publisher | Hindawi Publishing Corporation |
| record_format | eprints |
| spelling | my.ump.umpir.81762018-02-14T04:12:06Z http://umpir.ump.edu.my/id/eprint/8176/ Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones Sarkar, Shaheen M. Md. Eaqub, Ali Lutfor, M. R. M. M., Yusoff QD Chemistry Optically active (−)-ephedrine, (−)-norephedrine, and (−)-prolinol were immobilized onto cubicmesoporousMCM-48 silica. The immobilized amino alcohols served as a heterogeneous chiral catalyst for the asymmetric addition of diethylzinc to aldehydes and transfer hydrogenation to ketones. The developed catalytic process yielded optically enriches secondary aromatic alcohols with 92–99% conversion and 70–82% enantioselectivity. Hindawi Publishing Corporation Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/8176/1/Sha_JNM-3.pdf Sarkar, Shaheen M. and Md. Eaqub, Ali and Lutfor, M. R. and M. M., Yusoff Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones. Journal of Nanomaterials (Articl). pp. 1-6. ISSN 1687-4110 (print); 1687-4129 (online). (Published) |
| spellingShingle | QD Chemistry Sarkar, Shaheen M. Md. Eaqub, Ali Lutfor, M. R. M. M., Yusoff Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title | Preparation of Mesoporous Silica-Supported Chiral Amino
Alcohols for the Enantioselective Addition of Diethylzinc to
Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title_full | Preparation of Mesoporous Silica-Supported Chiral Amino
Alcohols for the Enantioselective Addition of Diethylzinc to
Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title_fullStr | Preparation of Mesoporous Silica-Supported Chiral Amino
Alcohols for the Enantioselective Addition of Diethylzinc to
Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title_full_unstemmed | Preparation of Mesoporous Silica-Supported Chiral Amino
Alcohols for the Enantioselective Addition of Diethylzinc to
Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title_short | Preparation of Mesoporous Silica-Supported Chiral Amino
Alcohols for the Enantioselective Addition of Diethylzinc to
Aldehyde and Asymmetric Transfer Hydrogenation to Ketones |
| title_sort | preparation of mesoporous silica-supported chiral amino
alcohols for the enantioselective addition of diethylzinc to
aldehyde and asymmetric transfer hydrogenation to ketones |
| topic | QD Chemistry |
| url | http://umpir.ump.edu.my/id/eprint/8176/1/Sha_JNM-3.pdf http://umpir.ump.edu.my/id/eprint/8176/ |
| url_provider | http://umpir.ump.edu.my/ |