Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone
The behavior of complex formation of Re(V) metal ion with azathioprine (AZ) and ceftriaxone (CE) as medicinal drugs has been investigated potentiometrically in 0.3 M hydrochloric acid. The stability constant of the prepared complexes has been determined and calculated at various temperatures. The ob...
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The Malaysian Analytical Sciences Society, UKM
2017
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| Online Access: | http://umpir.ump.edu.my/id/eprint/20177/2/37-Potentiometric%20Study%20of%20Rhenium%28V%29%20Complex%20Formation%20with%20Azathioprine%20and%20Ceftriaxone.pdf http://umpir.ump.edu.my/id/eprint/20177/ http://www.ukm.my/mjas/v21_n6/pdf/Gamal_21_6_8.pdf |
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| author | Gouda, Gamal Abdelaziz Hussein Ali, Gomaa A. M. |
| author_facet | Gouda, Gamal Abdelaziz Hussein Ali, Gomaa A. M. |
| author_sort | Gouda, Gamal Abdelaziz Hussein |
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| content_provider | Universiti Malaysia Pahang Al-Sultan Abdullah |
| content_source | UMPSA Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | The behavior of complex formation of Re(V) metal ion with azathioprine (AZ) and ceftriaxone (CE) as medicinal drugs has been investigated potentiometrically in 0.3 M hydrochloric acid. The stability constant of the prepared complexes has been determined and calculated at various temperatures. The obtained results showed that Re(V)-AZ system showed the formation 1:2, 1:3 and 1:4 complexes, while Re(V)-CE showed only 1:1 and 1:2 complexes. The complex formation suggests a successive displacement of the chloride molecules from the coordination sphere of the central ion by the AZ ligand. In addition, the effect of temperature on the complexes formation of Re(V) with AZ and CE was investigated. The entropy and enthalpy changes showed a favorable and exothermic process, respectively. The kinetic parameters of the formation complex process were calculated and discussed. |
| format | Article |
| id | my.ump.umpir.20177 |
| institution | Universiti Malaysia Pahang |
| language | en |
| publishDate | 2017 |
| publisher | The Malaysian Analytical Sciences Society, UKM |
| record_format | eprints |
| spelling | my.ump.umpir.201772018-01-18T01:28:52Z http://umpir.ump.edu.my/id/eprint/20177/ Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone Gouda, Gamal Abdelaziz Hussein Ali, Gomaa A. M. QD Chemistry The behavior of complex formation of Re(V) metal ion with azathioprine (AZ) and ceftriaxone (CE) as medicinal drugs has been investigated potentiometrically in 0.3 M hydrochloric acid. The stability constant of the prepared complexes has been determined and calculated at various temperatures. The obtained results showed that Re(V)-AZ system showed the formation 1:2, 1:3 and 1:4 complexes, while Re(V)-CE showed only 1:1 and 1:2 complexes. The complex formation suggests a successive displacement of the chloride molecules from the coordination sphere of the central ion by the AZ ligand. In addition, the effect of temperature on the complexes formation of Re(V) with AZ and CE was investigated. The entropy and enthalpy changes showed a favorable and exothermic process, respectively. The kinetic parameters of the formation complex process were calculated and discussed. The Malaysian Analytical Sciences Society, UKM 2017-12-01 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/20177/2/37-Potentiometric%20Study%20of%20Rhenium%28V%29%20Complex%20Formation%20with%20Azathioprine%20and%20Ceftriaxone.pdf Gouda, Gamal Abdelaziz Hussein and Ali, Gomaa A. M. (2017) Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone. Malaysian Journal of Analytical Sciences, 21 (6). pp. 1266-1275. ISSN 1394-2506. (Published) http://www.ukm.my/mjas/v21_n6/pdf/Gamal_21_6_8.pdf |
| spellingShingle | QD Chemistry Gouda, Gamal Abdelaziz Hussein Ali, Gomaa A. M. Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title | Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title_full | Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title_fullStr | Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title_full_unstemmed | Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title_short | Potentiometric Study of Rhenium(V) Complex Formation With Azathioprine And Ceftriaxone |
| title_sort | potentiometric study of rhenium(v) complex formation with azathioprine and ceftriaxone |
| topic | QD Chemistry |
| url | http://umpir.ump.edu.my/id/eprint/20177/2/37-Potentiometric%20Study%20of%20Rhenium%28V%29%20Complex%20Formation%20with%20Azathioprine%20and%20Ceftriaxone.pdf http://umpir.ump.edu.my/id/eprint/20177/ http://www.ukm.my/mjas/v21_n6/pdf/Gamal_21_6_8.pdf |
| url_provider | http://umpir.ump.edu.my/ |