Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Conference or Workshop Item |
| Language: | en |
| Published: |
2016
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf http://umpir.ump.edu.my/id/eprint/17064/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1831524603799797760 |
|---|---|
| author | E. N., Engku Mat Nasir Fatinah, Ab Rahman S., Abd Rahim Raihana Z., Edros N., Anuar |
| author_facet | E. N., Engku Mat Nasir Fatinah, Ab Rahman S., Abd Rahim Raihana Z., Edros N., Anuar |
| author_sort | E. N., Engku Mat Nasir |
| building | UMPSA Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaysia Pahang Al-Sultan Abdullah |
| content_source | UMPSA Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process is kinetics study. In this research, carbamazepine (CBZ) and co-former saccharin (SAC) has been used to study the metastable zone width (MSZW) of the CBZ-SAC co-crystal in ethanol solution. The MSZW is studied by varying concentration of CBZ, mo) ratio values of SAC to CBZ and cooling rates used by polythermal method. Crystallization temperature and dissolution temperature is used to determine the maximum temperature difference ~Tmax using N)'vlt's equation. |
| format | Conference or Workshop Item |
| id | my.ump.umpir.17064 |
| institution | Universiti Malaysia Pahang |
| language | en |
| publishDate | 2016 |
| record_format | eprints |
| spelling | my.ump.umpir.170642019-10-30T07:39:29Z http://umpir.ump.edu.my/id/eprint/17064/ Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal E. N., Engku Mat Nasir Fatinah, Ab Rahman S., Abd Rahim Raihana Z., Edros N., Anuar T Technology (General) TP Chemical technology Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process is kinetics study. In this research, carbamazepine (CBZ) and co-former saccharin (SAC) has been used to study the metastable zone width (MSZW) of the CBZ-SAC co-crystal in ethanol solution. The MSZW is studied by varying concentration of CBZ, mo) ratio values of SAC to CBZ and cooling rates used by polythermal method. Crystallization temperature and dissolution temperature is used to determine the maximum temperature difference ~Tmax using N)'vlt's equation. 2016 Conference or Workshop Item NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf E. N., Engku Mat Nasir and Fatinah, Ab Rahman and S., Abd Rahim and Raihana Z., Edros and N., Anuar (2016) Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal. In: The 18th International Conference on Crystal Growth and Epitaxy , 07-12 August 2016 , Nagoya, Japan. . (Unpublished) (Unpublished) |
| spellingShingle | T Technology (General) TP Chemical technology E. N., Engku Mat Nasir Fatinah, Ab Rahman S., Abd Rahim Raihana Z., Edros N., Anuar Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title | Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title_full | Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title_fullStr | Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title_full_unstemmed | Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title_short | Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal |
| title_sort | effect on operating parameters towards metastable zone width of carbamazepine-saccharin co-crystal |
| topic | T Technology (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf http://umpir.ump.edu.my/id/eprint/17064/ |
| url_provider | http://umpir.ump.edu.my/ |