Pyrimidine derivative as anti-liver cancer agent against EGFR Kinase Mutant T790M/L858R: a comprehensive in-silico approach

Liver cancer (LC) is the fourth most prevalent cause of cancer-related death worldwide. However, existing treatment options have limitations, as they do not consistently provide benefits to all patients. With an emphasis on pyrimidine derivatives, this study uses virtual screening approaches to find...

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Bibliographic Details

Main Authors:	Roney, Miah, Issahaku, Abdul Rashid, Uddin, Md. Nazim, Akter, Mahmuda, Wilhelm, Anke, Mohd Fadhlizil Fasihi, Mohd Aluwi
Format:	Article
Language:	en
Published:	Springer 2026
Subjects:	QD Chemistry RS Pharmacy and materia medica
Online Access:	https://umpir.ump.edu.my/id/eprint/47277/1/Pyrimidine%20derivative%20as%20anti-liver%20cancer%20agent.pdf https://doi.org/10.1007/s12247-025-10258-3 https://umpir.ump.edu.my/id/eprint/47277/
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