Parameter estimation in computational systems biology models: a comparative study of initialization methods in global optimization

This paper compares different initialization methods and investigates their performance and effects on estimating kinetic parameters’ value in models of biological systems. Estimating parameters values is difficult and time-consuming process due to their highly nonlinear and huge number of kinetic p...

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Bibliographic Details

Main Authors:	Muhammad Akmal, Remli, Nor Syahidatul Nadiah, Ismail, Noor Azida, Sahabudin, Nor Bakiah, Abd Warif
Format:	Article
Language:	en
Published:	The Science and Information (SAI) Organization Limited 2022
Subjects:	QA75 Electronic computers. Computer science TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/45597/1/Parameter%20estimation%20in%20computational%20systems%20biology%20models.pdf http://umpir.ump.edu.my/id/eprint/45597/ https://doi.org/10.14569/IJACSA.2022.0130854
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