Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches

Type 2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD) have similar clinical characteristics in the brain and islet, as well as an increased incidence with ageing and familial susceptibility. Therefore, in recent years there has been a great desire for research that elucidates how anti-diabeti...

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Main Authors:	Roney, Miah, Uddin, Md. Nazim, Khan, Azmat Ali, Fatima, Sabiha, Mohd Fadhlizil Fasihi, Mohd Aluwi, Hamim, S.M. Istiaque, Ahmad, Asrar
Format:	Article
Language:	en
Published:	Elsevier Ltd 2025
Subjects:	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RM Therapeutics. Pharmacology
Online Access:	http://umpir.ump.edu.my/id/eprint/45463/1/Repurposing%20of%20dipeptidyl%20peptidase%20FDA-approved%20drugs.pdf http://umpir.ump.edu.my/id/eprint/45463/ https://doi.org/10.1016/j.compbiolchem.2025.108378
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