Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei
The oxidative stress theory proposes that severe sepsis leads to activation of neutrophils and macrophages which subsequently release reactive oxygen-free radicals that may result in lipid peroxidation of endothelial and epithelial cell membrane phospholipids. This chain reaction results in increase...
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| Format: | Article |
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Stamford Publishing Pte Ltd / Singapore Medical Association
2008
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| Online Access: | http://eprints.um.edu.my/979/ http://www.ncbi.nlm.nih.gov/pubmed/18301838 |
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| _version_ | 1831446182075826176 |
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| author | Puthucheary, S.D. Nathan, S.A. |
| author_facet | Puthucheary, S.D. Nathan, S.A. |
| author_sort | Puthucheary, S.D. |
| building | UM Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaya |
| content_source | UM Research Repository |
| continent | Asia |
| country | Malaysia |
| description | The oxidative stress theory proposes that severe sepsis leads to activation of neutrophils and macrophages which subsequently release reactive oxygen-free radicals that may result in lipid peroxidation of endothelial and epithelial cell membrane phospholipids. This chain reaction results in increased levels of isoprostanes, which are thought to contribute to much of the end-stage tissue damage seen in serious infections, such as melioidosis. We believe that this is the first report linking in vivo oxidative stress status and diabetic patients infected with B. pseudomallei. |
| format | Article |
| id | my.um.eprints-979 |
| institution | Universiti Malaya |
| publishDate | 2008 |
| publisher | Stamford Publishing Pte Ltd / Singapore Medical Association |
| record_format | eprints |
| spelling | my.um.eprints-9792019-01-14T01:33:32Z http://eprints.um.edu.my/979/ Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei Puthucheary, S.D. Nathan, S.A. R Medicine (General) The oxidative stress theory proposes that severe sepsis leads to activation of neutrophils and macrophages which subsequently release reactive oxygen-free radicals that may result in lipid peroxidation of endothelial and epithelial cell membrane phospholipids. This chain reaction results in increased levels of isoprostanes, which are thought to contribute to much of the end-stage tissue damage seen in serious infections, such as melioidosis. We believe that this is the first report linking in vivo oxidative stress status and diabetic patients infected with B. pseudomallei. Stamford Publishing Pte Ltd / Singapore Medical Association 2008-02 Article PeerReviewed Puthucheary, S.D. and Nathan, S.A. (2008) Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei. Singapore Medical Journal, 49 (2). pp. 117-20. ISSN 0037-5675, DOI 18301838. http://www.ncbi.nlm.nih.gov/pubmed/18301838 18301838 |
| spellingShingle | R Medicine (General) Puthucheary, S.D. Nathan, S.A. Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title | Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title_full | Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title_fullStr | Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title_full_unstemmed | Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title_short | Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei |
| title_sort | comparison of serum f2 isoprostane levels in diabetic patients and diabetic patients infected with burkholderia pseudomallei |
| topic | R Medicine (General) |
| url | http://eprints.um.edu.my/979/ http://www.ncbi.nlm.nih.gov/pubmed/18301838 |
| url_provider | http://eprints.um.edu.my/ |