Lipase mediated synthesis of sugar fatty acid esters

This review is concerned with lipase catalyzed synthesis of sugar fatty acid esters in water immiscible organic solvents. Sugar esters are widely used nonionic and nontoxic biosurfactants. Certain sugar esters inhibit microbial growth and have other activities. Lipase mediated synthesis has import...

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Main Authors: Gumel, A.M., Annuar, M.S.M., Heidelberg, T., Chisti, Y.
Format: Article
Language:en
Published: Elsevier 2011
Subjects:
Online Access:http://eprints.um.edu.my/9637/1/00013161_103472.pdf
http://eprints.um.edu.my/9637/
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author Gumel, A.M.
Annuar, M.S.M.
Heidelberg, T.
Chisti, Y.
author_facet Gumel, A.M.
Annuar, M.S.M.
Heidelberg, T.
Chisti, Y.
author_sort Gumel, A.M.
building UM Library
collection Institutional Repository
content_provider Universiti Malaya
content_source UM Research Repository
continent Asia
country Malaysia
description This review is concerned with lipase catalyzed synthesis of sugar fatty acid esters in water immiscible organic solvents. Sugar esters are widely used nonionic and nontoxic biosurfactants. Certain sugar esters inhibit microbial growth and have other activities. Lipase mediated synthesis has important advantages over conventional chemical synthesis of sugar esters. Lipase catalyzed synthesis is typically carried out in organic solvents having a low water activity to drive the reaction towards synthesis instead of towards ester hydrolysis. The impact of the various reaction conditions on enzymatic synthesis of sugar esters in nonaqueous media is discussed. Considered in particular are the solvent effects; the effects of water activity; the influence of the nature and concentration of the reactants (sugars and fatty acids); the influence of temperature; and the effects associated with the specific nature of the lipase catalyst used.
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publishDate 2011
publisher Elsevier
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spelling my.um.eprints-96372014-04-22T02:19:39Z http://eprints.um.edu.my/9637/ Lipase mediated synthesis of sugar fatty acid esters Gumel, A.M. Annuar, M.S.M. Heidelberg, T. Chisti, Y. Q Science (General) QD Chemistry This review is concerned with lipase catalyzed synthesis of sugar fatty acid esters in water immiscible organic solvents. Sugar esters are widely used nonionic and nontoxic biosurfactants. Certain sugar esters inhibit microbial growth and have other activities. Lipase mediated synthesis has important advantages over conventional chemical synthesis of sugar esters. Lipase catalyzed synthesis is typically carried out in organic solvents having a low water activity to drive the reaction towards synthesis instead of towards ester hydrolysis. The impact of the various reaction conditions on enzymatic synthesis of sugar esters in nonaqueous media is discussed. Considered in particular are the solvent effects; the effects of water activity; the influence of the nature and concentration of the reactants (sugars and fatty acids); the influence of temperature; and the effects associated with the specific nature of the lipase catalyst used. Elsevier 2011 Article PeerReviewed application/pdf en http://eprints.um.edu.my/9637/1/00013161_103472.pdf Gumel, A.M. and Annuar, M.S.M. and Heidelberg, T. and Chisti, Y. (2011) Lipase mediated synthesis of sugar fatty acid esters. Process Biochemistry, 46. pp. 2079-2090. DOI https://doi.org/10.1016/j.procbio.2011.07.021 <https://doi.org/10.1016/j.procbio.2011.07.021>. doi:10.1016/j.procbio.2011.07.021
spellingShingle Q Science (General)
QD Chemistry
Gumel, A.M.
Annuar, M.S.M.
Heidelberg, T.
Chisti, Y.
Lipase mediated synthesis of sugar fatty acid esters
title Lipase mediated synthesis of sugar fatty acid esters
title_full Lipase mediated synthesis of sugar fatty acid esters
title_fullStr Lipase mediated synthesis of sugar fatty acid esters
title_full_unstemmed Lipase mediated synthesis of sugar fatty acid esters
title_short Lipase mediated synthesis of sugar fatty acid esters
title_sort lipase mediated synthesis of sugar fatty acid esters
topic Q Science (General)
QD Chemistry
url http://eprints.um.edu.my/9637/1/00013161_103472.pdf
http://eprints.um.edu.my/9637/
url_provider http://eprints.um.edu.my/