Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial
BACKGROUND: Hypertension is the number one cardiovascular risk factor in Malaysia. This study aimed to evaluate the effectiveness of a Community-Based Cardiovascular Risk Factors Intervention Strategies (CORFIS) in the management of hypertension in primary care. METHODS: This is a pragmatic, non-ran...
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2013
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| Online Access: | http://eprints.um.edu.my/9062/1/Community-based_cardiovascular_Risk_Factors_Intervention_Strategies_%28CORFIS%29_in_managing_hypertension-A_pragmatic_non-randomised_controlled_trial.pdf http://eprints.um.edu.my/9062/ http://www.e-mjm.org/2013/v68n2/CORFIS-in-managing-hypertension.pdf |
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| author | Low, W.H.H. Seet, W. Ramli, A.S. Ng, K.K. Jamaiyah, H. Dan, S.P. Teng, C.L. Lee, V.K.M. Chua, S.S. Faridah Aryani, M.Y. Karupaiah, T. Chee, W.S.S. Goh, P.P. Zaki, M. Lim, T.O. |
| author_facet | Low, W.H.H. Seet, W. Ramli, A.S. Ng, K.K. Jamaiyah, H. Dan, S.P. Teng, C.L. Lee, V.K.M. Chua, S.S. Faridah Aryani, M.Y. Karupaiah, T. Chee, W.S.S. Goh, P.P. Zaki, M. Lim, T.O. |
| author_sort | Low, W.H.H. |
| building | UM Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaya |
| content_source | UM Research Repository |
| continent | Asia |
| country | Malaysia |
| description | BACKGROUND: Hypertension is the number one cardiovascular risk factor in Malaysia. This study aimed to evaluate the effectiveness of a Community-Based Cardiovascular Risk Factors Intervention Strategies (CORFIS) in the management of hypertension in primary care. METHODS: This is a pragmatic, non-randomized controlled trial. Seventy general practitioners (GPs) were selected to provide either CORFIS (44 GPs) or conventional care (26 GPs) for 6 months. A total of 486 hypertensive patients were recruited; 309 were in the intervention and 177 in the control groups. Primary outcome was the proportion of hypertensive patients who achieved target blood pressure (BP) of <140/90mmHg (for those without diabetes mellitus) and <130/80mmHg (with diabetes mellitus). Secondary outcomes include change in the mean/median BP at 6-month as compared to baseline. RESULTS: The proportion of hypertensive patients who achieved target BP at 6-month was significantly higher in the CORFIS arm (69.6) as compared to the control arm (57.6), P=0.008. Amongst those who had uncontrolled BP at baseline, the proportion who achieved target BP at 6-month was also significantly higher in the CORFIS arm (56.6) as compared to the control arm (34.1), p<0.001. There was no difference in the patients who had already achieved BP control at baseline. There were significant reductions in SBP in the CORFIS arm (median -9.0mmHg; -60 to 50) versus control (median -2mmHg; -50 to 48), p=0.003; as well as in DBP (CORFIS arm: median -6.0mmHg; ranged from -53 to 30 versus control arm: median 0.0mmHg; ranged from -42 to 30), p<0.001. CONCLUSIONS: Patients who received CORFIS care demonstrated significant improvements in achieving target BP. |
| format | Article |
| id | my.um.eprints-9062 |
| institution | Universiti Malaya |
| language | en |
| publishDate | 2013 |
| record_format | eprints |
| spelling | my.um.eprints-90622014-12-16T09:13:36Z http://eprints.um.edu.my/9062/ Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial Low, W.H.H. Seet, W. Ramli, A.S. Ng, K.K. Jamaiyah, H. Dan, S.P. Teng, C.L. Lee, V.K.M. Chua, S.S. Faridah Aryani, M.Y. Karupaiah, T. Chee, W.S.S. Goh, P.P. Zaki, M. Lim, T.O. R Medicine BACKGROUND: Hypertension is the number one cardiovascular risk factor in Malaysia. This study aimed to evaluate the effectiveness of a Community-Based Cardiovascular Risk Factors Intervention Strategies (CORFIS) in the management of hypertension in primary care. METHODS: This is a pragmatic, non-randomized controlled trial. Seventy general practitioners (GPs) were selected to provide either CORFIS (44 GPs) or conventional care (26 GPs) for 6 months. A total of 486 hypertensive patients were recruited; 309 were in the intervention and 177 in the control groups. Primary outcome was the proportion of hypertensive patients who achieved target blood pressure (BP) of <140/90mmHg (for those without diabetes mellitus) and <130/80mmHg (with diabetes mellitus). Secondary outcomes include change in the mean/median BP at 6-month as compared to baseline. RESULTS: The proportion of hypertensive patients who achieved target BP at 6-month was significantly higher in the CORFIS arm (69.6) as compared to the control arm (57.6), P=0.008. Amongst those who had uncontrolled BP at baseline, the proportion who achieved target BP at 6-month was also significantly higher in the CORFIS arm (56.6) as compared to the control arm (34.1), p<0.001. There was no difference in the patients who had already achieved BP control at baseline. There were significant reductions in SBP in the CORFIS arm (median -9.0mmHg; -60 to 50) versus control (median -2mmHg; -50 to 48), p=0.003; as well as in DBP (CORFIS arm: median -6.0mmHg; ranged from -53 to 30 versus control arm: median 0.0mmHg; ranged from -42 to 30), p<0.001. CONCLUSIONS: Patients who received CORFIS care demonstrated significant improvements in achieving target BP. 2013 Article PeerReviewed application/pdf en http://eprints.um.edu.my/9062/1/Community-based_cardiovascular_Risk_Factors_Intervention_Strategies_%28CORFIS%29_in_managing_hypertension-A_pragmatic_non-randomised_controlled_trial.pdf Low, W.H.H. and Seet, W. and Ramli, A.S. and Ng, K.K. and Jamaiyah, H. and Dan, S.P. and Teng, C.L. and Lee, V.K.M. and Chua, S.S. and Faridah Aryani, M.Y. and Karupaiah, T. and Chee, W.S.S. and Goh, P.P. and Zaki, M. and Lim, T.O. (2013) Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial. Medical Journal of Malaysia, 68 (2). pp. 129-35. ISSN 0300-5283, http://www.e-mjm.org/2013/v68n2/CORFIS-in-managing-hypertension.pdf |
| spellingShingle | R Medicine Low, W.H.H. Seet, W. Ramli, A.S. Ng, K.K. Jamaiyah, H. Dan, S.P. Teng, C.L. Lee, V.K.M. Chua, S.S. Faridah Aryani, M.Y. Karupaiah, T. Chee, W.S.S. Goh, P.P. Zaki, M. Lim, T.O. Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title | Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title_full | Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title_fullStr | Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title_full_unstemmed | Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title_short | Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial |
| title_sort | community-based cardiovascular risk factors intervention strategies (corfis) in managing hypertension: a pragmatic non-randomised controlled trial |
| topic | R Medicine |
| url | http://eprints.um.edu.my/9062/1/Community-based_cardiovascular_Risk_Factors_Intervention_Strategies_%28CORFIS%29_in_managing_hypertension-A_pragmatic_non-randomised_controlled_trial.pdf http://eprints.um.edu.my/9062/ http://www.e-mjm.org/2013/v68n2/CORFIS-in-managing-hypertension.pdf |
| url_provider | http://eprints.um.edu.my/ |