Chikungunya virus-associated death in Malaysia

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes fever, rash, and arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications and deaths. Mala...

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Bibliographic Details
Main Authors: Sam, I.C., Kamarulzaman, Adeeba, Ong, G.S.Y., Veriah, R.S., Ponnampalavanar, S., Chan, Y.F., AbuBakar, Sazaly
Format: Article
Language:en
Published: 2007
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Online Access:http://eprints.um.edu.my/4543/1/Chikungunya_virus-associated_death_in_Malaysia.pdf
http://eprints.um.edu.my/4543/
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Summary:Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes fever, rash, and arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications and deaths. Malaysia is experiencing a nationwide outbreak of CHIKV, with over 10 000 patients affected since April 2008. We report the first case of culture-confirmed CHIKV-associated death in Malaysia, in a patient with fever, rash, acute exacerbation of pre-existing heart failure, rhabdomyolysis, and multiple organ failure. CHIKV infections may cause atypical, severe or fatal presentations.