C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma

C-kit is a trans-membrane receptor tyrosine kinase (RTK) encoded by the proto-oncogene KIT located at 4q11-12. Gain-of-function mutations arising to c-kit activation independent of its ligand were observed in various tumors related to germ cells, mast cells, and interstitial cells of Cajal. C-kit al...

Full description

Bibliographic Details

Main Authors:	Rivera, R.S., Nagatsuka, H., Gunduz, M., Cengiz, B., Gunduz, E., Siar, C.H., Tsujigiwa, H., Tamamura, R., Han, K.N., Nagai, N.
Format:	Article
Language:	en
Published:	2008
Subjects:	RK Dentistry
Online Access:	http://eprints.um.edu.my/4310/1/C-kit_protein_expression_correlated_with_activating_mutations_in_KIT_gene_in_oral_mucosal_melanoma.pdf http://eprints.um.edu.my/4310/
Tags:	Add Tag No Tags, Be the first to tag this record!