Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia
Species identification of human hookworm infections among eight communities in rural areas of Peninsular Malaysia was determined during 2009-2011. Fecal samples were examined by microscopy and subsequently, the internal transcribed spacer 2 and 28S ribosomal RNA region of Necator americanus and Ancy...
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American Society of Tropical Medicine and Hygiene
2012
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| Online Access: | http://eprints.um.edu.my/4049/ http://www.ncbi.nlm.nih.gov/pubmed/22556084 |
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| author | Ngui, R. Ching, L. S. Kai, T. T. Roslan, M. A. Lim, Y. A. L. |
| author_facet | Ngui, R. Ching, L. S. Kai, T. T. Roslan, M. A. Lim, Y. A. L. |
| author_sort | Ngui, R. |
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| content_provider | Universiti Malaya |
| content_source | UM Research Repository |
| continent | Asia |
| country | Malaysia |
| description | Species identification of human hookworm infections among eight communities in rural areas of Peninsular Malaysia was determined during 2009-2011. Fecal samples were examined by microscopy and subsequently, the internal transcribed spacer 2 and 28S ribosomal RNA region of Necator americanus and Ancylostoma spp. were sequenced. Overall, 9.1 (58 of 634) were identified positive by microscopy for hookworm infection, and 47 (81.0) of 58 were successfully amplified and sequenced. Sequence comparison found that N. americanus (87.2) was the most predominant hookworm identified, followed by Ancylostoma ceylanicum (23.4). No A. duodenale infection was detected in this study. Detection of A. ceylanicum in humans highlighted the zoonotic transmission among humans living near dogs. Thus, implementation of effective control measures for hookworm infections in future should seriously consider this zoonotic implication. |
| format | Article |
| id | my.um.eprints-4049 |
| institution | Universiti Malaya |
| publishDate | 2012 |
| publisher | American Society of Tropical Medicine and Hygiene |
| record_format | eprints |
| spelling | my.um.eprints-40492025-04-11T01:17:54Z http://eprints.um.edu.my/4049/ Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia Ngui, R. Ching, L. S. Kai, T. T. Roslan, M. A. Lim, Y. A. L. R Medicine Species identification of human hookworm infections among eight communities in rural areas of Peninsular Malaysia was determined during 2009-2011. Fecal samples were examined by microscopy and subsequently, the internal transcribed spacer 2 and 28S ribosomal RNA region of Necator americanus and Ancylostoma spp. were sequenced. Overall, 9.1 (58 of 634) were identified positive by microscopy for hookworm infection, and 47 (81.0) of 58 were successfully amplified and sequenced. Sequence comparison found that N. americanus (87.2) was the most predominant hookworm identified, followed by Ancylostoma ceylanicum (23.4). No A. duodenale infection was detected in this study. Detection of A. ceylanicum in humans highlighted the zoonotic transmission among humans living near dogs. Thus, implementation of effective control measures for hookworm infections in future should seriously consider this zoonotic implication. American Society of Tropical Medicine and Hygiene 2012 Article PeerReviewed Ngui, R. and Ching, L. S. and Kai, T. T. and Roslan, M. A. and Lim, Y. A. L. (2012) Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia. American Journal of Tropical Medicine and Hygiene, 86 (5). pp. 837-842. ISSN 0002-9637, DOI https://doi.org/10.4269/ajtmh.2012.11-0446 <https://doi.org/10.4269/ajtmh.2012.11-0446>. http://www.ncbi.nlm.nih.gov/pubmed/22556084 10.4269/ajtmh.2012.11-0446 |
| spellingShingle | R Medicine Ngui, R. Ching, L. S. Kai, T. T. Roslan, M. A. Lim, Y. A. L. Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title | Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title_full | Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title_fullStr | Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title_full_unstemmed | Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title_short | Molecular identification of human hookworm infections in economically disadvantaged communities in peninsular Malaysia |
| title_sort | molecular identification of human hookworm infections in economically disadvantaged communities in peninsular malaysia |
| topic | R Medicine |
| url | http://eprints.um.edu.my/4049/ http://www.ncbi.nlm.nih.gov/pubmed/22556084 |
| url_provider | http://eprints.um.edu.my/ |