Genotype-Phenotype diversity of Beta-Thalassemia in Malaysia: treatment options and emerging therapies
The haemoglobinopathies and thalassemias represent the most common inherited monogenic disorders in the world. Beta-thalassaemia major is an ongoing public health problem in Malaysia. Prior to 2004, the country had no national policy for screening and registry for thalassemia. In the absence of a na...
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| Main Authors: | , |
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| Format: | Article |
| Language: | en |
| Published: |
Malaysian Medical Association
2010
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/3710/1/Genotype-phenotype_diversity_of_beta-thalassaemia.pdf http://eprints.um.edu.my/3710/ |
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| Summary: | The haemoglobinopathies and thalassemias represent the most common inherited monogenic disorders in the world. Beta-thalassaemia major is an ongoing public health problem in Malaysia. Prior to 2004, the country had no national policy for screening and registry for thalassemia. In the absence of a national audit, the true figure of the extent of thalassemia in the Malaysian population was largely presumptive from micro-mapping studies from various research workers in the country. The estimated carrier rate for beta-thalassemia in Malaysia is 3.5-4. There were 4768 transfusion dependent thalassemia major patients as of May 2010 (Data from National Thalassemia Registry). |
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