Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts

The dichloromethane (DCM) extract of Andrographis paniculata Nees was tested for cardiovascular activity. The extract significantly reduced coronary perfusion pressure by up to 24.5 ± 3.0 mm Hg at a 3 mg dose and also reduced heart rate by up to 49.5 ± 11.4 beats/minute at this dose. Five labdane di...

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Bibliographic Details

Main Authors:	Awang, Khalijah, Abdullah, N.H., Hadi, A.H., Su Fong, Y.
Format:	Article
Language:	en
Published:	Hindawi Publishing Corporation 2012
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/3168/1/1.pdf http://eprints.um.edu.my/3168/ http://www.ncbi.nlm.nih.gov/pubmed/22536026
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