Synthesis and evaluation of chromone-2-carboxamido-alkylamines as potent acetylcholinesterase inhibitors

Alzheimer’s disease (AD) is considered one of the greatest global public burdens. Pathophysiology of AD is proposed to be associated with reduced levels of the neurotransmitter acetylcholine (ACh). Cholinesterase enzymes, namely acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) cleave ACh...

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Bibliographic Details

Main Authors:	Suwanhom, Paptawan, Nualnoi, Teerapat, Khongkow, Pasarat, Lee, Vannajan Sanghiran, Lomlim, Luelak
Format:	Article
Published:	Springer Verlag 2020
Subjects:	Q Science (General) QD Chemistry R Medicine
Online Access:	http://eprints.um.edu.my/24859/ https://doi.org/10.1007/s00044-020-02508-5
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