Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells

Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to agerelated vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. Th...

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Bibliographic Details

Main Authors:	Wong, Pooi Fong, Tong, Kind Leng, Jamal, Juliana, Khor, Eng Soon, Lai, Siew Li, Mustafa, Mohd Rais
Format:	Article
Published:	Leibniz Research Centre for Working Environment and Human Factors 2019
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/23160/ https://www.excli.de/vol18/Wong_03092019_proof.pdf
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