Near-Infrared Activatable Phthalocyanine–Poly-L-Glutamic Acid Conjugate: Enhanced in Vivo Safety and Antitumor Efficacy toward an Effective Photodynamic Cancer Therapy

We previously developed a new zinc(II) phthalocyanine (ZnPc) derivative (Pc 1) conjugated to poly-L-glutamic acid (PGA) (1-PG) to address the limitations of ZnPc as part of an antitumor photodynamic therapy approach, which include hydrophobicity, phototoxicity, and nonselectivity in biodistribution...

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Main Authors:	Cheah, Hoay Yan, Gallon, Elena, Dumoulin, Fabienne, Hoe, See Ziau, Japundžić-Žigon, Nina, Glumac, Sofija, Lee, Hong Boon, Anand, Prem, Chung, Lip Yong, Vicent, Maria Jesus, Kiew, Lik Voon
Format:	Article
Published:	American Chemical Society 2018
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/22261/ https://doi.org/10.1021/acs.molpharmaceut.8b00132
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