Deciphering critical amino acid residues to modify and enhance the binding affinity of ankyrin scaffold specific to capsid protein of human immunodeficiency virus type 1

Background: Ank GAG 1D4 is an artificial ankyrin repeat protein which recognizes the capsid protein (CA) of the human immunodeficiency virus type 1 (HIV-1) and exhibits the intracellular antiviral activity on the viral assembly process. Improving the binding affinity of Ank GAG 1D4 would potentially...

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Main Authors:	Saoin, Somphot, Wisitponchai, Tanchanok, Intachai, Kannaporn, Chupradit, Koollawat, Moonmuang, Sutpirat, Nangola, Sawitree, Kitidee, Kuntida, Fanhchaksai, Kanda, Lee, Vannajan Sanghiran, Hong, Saw See, Boulanger, Pierre, Chuankhayan, Phimonphan, Chen, Chun Jung, Tayapiwatana, Chatchai
Format:	Article
Published:	Allergy and Immunology Society of Thailand 2017
Subjects:	Q Science (General) QC Physics QD Chemistry R Medicine
Online Access:	http://eprints.um.edu.my/20771/ https://doi.org/10.12932/AP-280217-0037
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