PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation

Crosstalk between the phosphatidylinositol 3-kinase (PI3K) and the transforming growth factor-β signalling pathways play an important role in regulating many cellular functions. However, the molecular mechanisms underpinning this crosstalk remain unclear. Here, we report that PI3K signalling antagon...

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Bibliographic Details

Main Authors:	Yu, J.S.L., Ramasamy, T.S., Murphy, N., Holt, M.K., Czapiewski, R., Wei, S.K., Cui, W.
Format:	Article
Published:	Nature Publishing Group 2015
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/19339/ http://dx.doi.org/10.1038/ncomms8212
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